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Reaction To Enfuvirtide

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Get the Facts
AIDS InfoNet

Enfuvirtide (Fuzeon)

...It can take about 40 minutes to prepare a dose of enfuvirtide. You can prepare both of a day's doses at the same time. Avoid injecting near large nerves (ask your health care provider). Also, dont inject where you have had a reaction from a previous injection or into moles, tattoos, scar tissue, bruises, or your navel. A new injector (the Biojector) was considered for use with enfuvirtide. However, in October 2007 Roche stopped trying to get...
Ask the Experts

Injection of T-20 (Enfuvirtide)

Hello, I'm a physician treating a patient with T-20. The injections have been causing him reactions at the site - namely erythema, nodules, pruritus, ecchymosis, pain and discomfort. What techniques do you use or recommend to lessen these ISR's? ...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
Some patients have reported less ISRs with use of the BioInjector system for Fuzeon (an air gun). Cooling the inject site with ice packs for some while for others heat/message has helped. Since there likely will be a number of new HIV drugs active... Read more »

Tried almost everything

My name is Patrick. I'm 49 and I was diagnosed as HIV+ in 1989. I probably seroconverted sometime between 1983 and 1986. I started therapy in 1990. So far, I've been on all available meds and combinations and am resistant to essentially...
Renslow Sherer, M.D.

Response from Renslow Sherer, M.D.

University of Chicago Hospitals
...could consider removing ENF in future if and when you are able to achieve full control with this new regimen, and if the skin reactions were becoming a burden. Even in patients who have been on enfurvitide for a while, it appears that the drug... Read more »

stubborn numbers checking in

Hi Dr Young,How are you? I still check in to read your forum sometimes. You always make me smile. Thank you so much. I thought you might like an update (I'm "stubborn numbers" from back in Aug/Sept) My numbers are 186 (15%) and 180,000. Previously...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
...slight decrease in your viral load; nevertheless, the slight increase in your CD4 is in the right direction. Injection site reactions can dog treatment with enfuvirtide (T20, Fuzeon)-- rotating the sites and massage can help; though for some... Read more »

How long do I stay on Fuzeon

I started treatment in 1987, and am resistant to most drugs. Thankfully, ART has kept my CD4 count in the 300s and my viral load below 1000 even though my genotype and phenotype show resistance. My physician added Fuzeon to my regimen two years...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
...Thanks for your post.HIV can pretty quickly develop resistance to enfuvirtide (T20, Fuzeon) if used with a non-suppressive treatment regimen. While your viral load is low, it's above the 500 copy level Read more »
Articles
The Body PRO

Odds and Ends From CROI 2005: CD4+ Testing, Enfuvirtide Site Reactions, Erectile Dysfunction and Cancers

...standard CD4+ cell tests: It provides a CD4+ cell count, as well as a CD4+ cell percentage and total white blood cell count, in about 20 minutes. It requires no specific training for its use. It has the advantage of providing immediate results to... Read more »
AIDSinfo

An Overview of Fuzeon (Enfuvirtide, T-20)

... en-FYOO-vir-tide --> Brand Name: Fuzeon Other Name(s): DP 178, DP178, Enfuvirtida, Pentafuside, T 20, T-20, T20 Drug Class: Entry and Fusion Inhibitors Enfuvirtide, also known as Fuzeon or T-20, is a type of medicine called Read more »
Project Inform

Bottom Line on the Three New Drugs

...people with multi-drug resistance to other anti-HIV therapies. It appears safe, with the primary side effect of injection site reactions. Enfuvirtide appears to be active and useful for people who have failed other therapies and represents a... Read more »
Test Positive Aware Network

Fuzeon

..., www.fuzeon.com , 1 (877) 4-FUZEON (438-9366) Potential side effects and toxicity: The most common are Injection Site Reactions (ISRs), which occur in virtually all patients. The severity of reaction is variable, and for most is mild to... Read more »
Connect With Others

my strange reaction

Posted by midwestguy143, 2 Replies
...I tested positive on March 24, 2009. The thing that surprised me, and my friends was my reaction -- none really. Just something else in my life. I had lost my job many months ago, and with the job market being so tough, Read more »

ISR's w/T-20 Fuzeon suck

Posted by Scoot2Bfree, 3 Replies
It's a total pisser when you run out of spaces for injections. Have lipoatropahy, no body fat, ISR's are horrible but Dr's say last option as it's salvage therapy. Doing the Tibotec Duet TMC 125 NNRTI with/possible TMC 114 NRTI (placebo trial) thing... Read more »

information

Posted by Anonymous, 1 Reply
...also cause inflammation of the pancreas and painful nerve damage. There have been reports of complications and other severe reactions, including death, to some of the antiretroviral nucleoside analogs when used alone or in combination. Therefore,... Read more »

allergic reactions

Posted by TRex, 2 Replies
...Has anyone who is HIV positive had a lot of allergic reactiosn to antibiotics? I had two allergic reactions (the Bactrim one was the one who made me ask for the HIV test).the other one is Keflex. I am on Augmentin now and woke up with Read more »