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Reaction To Didanosine

Here's a taste of what has to offer on this topic:
Get the Facts
AIDS InfoNet

Taking Current Antiretroviral Drugs

...(Nukes) Drug Daily Pills (Adults) * How to Take and Store Side Effects Notes Abacavir (Ziagen) 2 (300 mg: 1, 2x/day or 2, 1x/day) No food restrictions; alcohol boosts abacavir levels. Hypersensitivity reaction in about 8% of patients Don't use with ust two other nucleoside analogs unless additional drugs are used. Combivir (Combination pill) 2 (150 mg lamivudine + 300 mg zidovudine: 1, 2x/day) No food...
Ask the Experts

RE: Second line regimen

Dear Dr. Joe, many thanks for the concern and well-thought answer to my inquiry about regarding sister's change of medication. As a follow up to my question which is attached under along with your answer, I would like to inform you that even with...
Joseph McGowan, M.D., F.A.C.P.

Response from Joseph McGowan, M.D., F.A.C.P.

North Shore University Hospital
...combo.If her virus is fully suppressed and she is still getting thinner, there is a possibility that it could be a metabolic reaction to the medications, called lipoatrophy. This is when the fat under the skin is lost due to a side effect of... Read more »

resistance test

I have been poz since 1982, hereunder the drugs i have been taking for 12 years Atripla (efavirenz + tenofovir + emtricitabine) Combivir (zidovudine + lamivudine, AZT + 3TC) Videx (didanosine, ddI) Crixivan (indinavir, IDV) Invirase (saquinavir,...
Mark Holodniy, M.D., F.A.C.P., C.I.C.

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine
If you are still on any of the HIV meds you listed, you need to change them and get your CD4 count up and your viral load to undetectable. I would favor something like darunavir/ritonavir + raltegravir + truvada. Read more »

Having children

HiI have recently started treatment for approx. 1 mth now and taking stocrin and avocomb. I was told that i should avoid getting pregnant. Can i change my meds and if so what are your suggestions. cd4 is 240
Joseph McGowan, M.D., F.A.C.P.

Response from Joseph McGowan, M.D., F.A.C.P.

North Shore University Hospital
...initiated in pregnant women with CD4 counts below 250 due to an increased risk of hepatitis and hypersensitivity (severe allergic) reactions. There are safer alternatives that could be considered, you should discuss your plans and the options... Read more »

GI side effects

Which HIV treatment for initial therapy, on the preferred list, has the most gastrointestinal side effects?
Brian Conway, M.D.

Response from Brian Conway, M.D.

University of British Columbia
...these types of things to occur with didanosine and zidovudine. They could also happen as part of the abacavir hypersensitivity reaction. Lamivudine and emtricitabine are particularly safe.Among the NNRTIs, you can see nausea and vomiting with... Read more »
Brown Medical School

HIV 101: Common Toxicities Among ARVs

...Ziagen) Mitochondrial toxicity (pancreatitis, peripheral neuropathy, lactic acidosis) and lipodystrophy Hypersensitivity reaction Didanosine (ddI, Videx) Mitochondrial toxicity (pancreatitis, peripheral neuropathy, lactic acidosis) and... Read more »
U.S. Food and Drug Administration

Early Communication About an Ongoing Safety Review of Ziagen (Abacavir) and Videx (Didanosine)

...and recommendations to the public. The FDA urges healthcare professionals to promptly report serious and unexpected adverse reactions associated with abacavir and didanosine, and all drugs, to the FDA MedWatch reporting program, as described... Read more »
AIDS InfoNet

Stavudine (Zerit)

...healthier longer. Pregnant women face special risks when taking stavudine. See the information below on lactic acidosis and drug reactions. What About Drug Resistance? Many new copies of HIV are mutations. They are slightly different from the... Read more »
The Well Project

HIV Drugs and the HIV Lifecycle

...cell in a processcalled fusion. After fusion, HIV releases its RNA (genetic material) andenzymes (proteins that cause chemical reactions) into the CD4 cell. Reverse Transcription HIV's RNA contains the "instructions" that... Read more »
Connect With Others


Posted by Anonymous
...after the infection is acquired. On the other hand, the quantitative plasma HIV-1 RNA level (viral load) by polymerase chain reaction (PCR), which is 95 to 98 percent sensitive for HIV,8 becomes positive within 11 days of infection.9 During the... Read more »

Starting meds for the first time.

Posted by glowstixboyoh, 15 Replies
Hi everyone. I am a little angry right now. I was diagnosed poz on march first of this year. I just got my lab results back and people think I should start meds. Its seems to them the virus is newly aquired, but it also looks like my immune... Read more »

Does anyone feel good on meds??

Posted by Anonymous, 6 Replies
I found out I was HIV pos last year. Doing well, feeling great, normal CD4 and percentages and VL less than 1500 on three tests. No meds needed yet per my HIV doc. Reading the posts here and letters to the experts it seems everyone is having... Read more »

allergic reactions

Posted by TRex, 2 Replies
...Has anyone who is HIV positive had a lot of allergic reactiosn to antibiotics? I had two allergic reactions (the Bactrim one was the one who made me ask for the HIV test).the other one is Keflex. I am on Augmentin now and woke up with Read more »