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Quantifying Hiv Specific B Cells

Here's a taste of what TheBody.com has to offer on this topic:
Ask the Experts

quantifying viral load

Is viral load determined before or after PCR amplification? The reason I ask is that I see "50 perMl" given as the number at which the virus is undetectable, and that would mean that before PCR virtually everyone who is HIV positive is...
Mark Holodniy, M.D., F.A.C.P., C.I.C.

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine
A 50 copy viral load is what is there before PCR. An internal standard of known copy number is added to each patients sample of unknown copy number. Based on the signal obtained in a PCR assay for the known standard, the patient copy number is... Read more »

Specific cells HIV infect or not

I know that HIV does not infect vaginal epithelial cells, but what specific cell types does HIV... Read more »

early treatment and hiv-specific T cells

Dear Dr. Young,I have read about the studies of Walker et al. with great interest, and I think... Read more »
Articles
Treatment Action Group

Antiviral Activity of Virus-Specific CD8 T Cells Linked to Rate of CD4 T Cell Decline in HIV Infection

The extent to which virus-specific CD8 T cell responses contribute to control of viral load and prevention of disease progression in HIV infection has long been a subject of conflicting data and controversy. Early tests of the ability of CD8 T cells... Read more »
Treatment Action Group

CD4 T Cells Specific for Different Pathogens Vary in Susceptibility to HIV Infection

When it comes to susceptibility to HIV infection, not all CD4 T cells are created equal. There are a variety of factors that have been shown to influence how readily HIV gains entry and replicates, with the best-described distinction being between... Read more »
TheBodyPRO.com

Interleukin-2 Expands Select CD4+ T-Cell Populations, but Has No Effect on HIV-Specific Immune Responses

Previous studies have shown that the use of interleukin-2 (IL-2) in HIV-infected persons on antiretroviral therapy generally increases naive and central memory CD4+ T cells. The French ANRS 119 study is a randomized trial assessing whether the use... Read more »
Treatment Action Group

Gene Modification of Virus-Specific CD4 T Cells

Patrick Younan from the Fred Hutchinson Cancer ResearchCenter delivered an interesting talk about transplantation of gene-modifiedstem cells in pigtailed macaques (abstract , webcast -- third in session). The experiment used lentiviralvectors to... Read more »
Connect With Others

Some specific questions I didn't came across, ever / and something interesting

Posted by absger, 2 Replies
First question:

The CDC says that HIV can be transmitted trough "small cuts or open sours".

I am sure that there are a lot of people out there that shave their "triangle" last-minute, e.g. minutes before the sexual act. Everybody knows that body... Read more »

HIV-Specific Medications AT COST - a new service

Posted by CanDoMeds, 1 Reply
To The Body Forum users,

Please allow me to introduce a new public service that my company is offering to HIV-positive patients. My business partner, Dr. Mark Galea, and I have decided to create a special program for certain medical populations, and... Read more »

Non-specific?????????

Posted by Anonymous, 2 Replies
tested negative for hiv and syphillis, hep b,c past six month period but have several strange markings like bruises(red spots) on palms of hand and soles of feet. Any help would be appreciated. Thanks GOD Bless all.

Read more »

T-CELL COUNT

Posted by Anonymous, 1 Reply
Hiv negative but still worried.
I took a T-CELL count which came back as follows:

TOTAL LYMPH. 2630

CD3+ 2090 - 79.4%
CD4+ 1010 - 38.4%
CD5+ 72.8%
CD8+ 1157 - 44.0%

RATIO CD4+/CD8+ 0.87

What does this mean? Can these results be influenced by the... Read more »

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