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Protease Inhibitors Mechanism Of Action

Here's a taste of what TheBody.com has to offer on this topic:
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AIDS InfoNet

Protease Inhibitors in Development

... Protease Inhibitors Protease Inhibitors in Development PIs No Longer in Development NOTE: Several fact sheets describe drugs that are being tested against HIV: Fact Sheet 410 : nucleoside analog reverse transcriptase inhibitors (nukes)
Ask the Experts

Interactions of Protease Inhibitors and Blood Pressure Medications

I was recently placed on Tekturna and HCT to treat my blood pressure, and pravastatin for the P.I. increased cholesterol.Initially, the Tekturna dose of 150mg (the lowest prescription) seemed to create a neuropathy sensation on my left leg and arm. ...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
...I have seen no formal drug interaction studies with protease inhibitors and Aliskiren but the potential for interaction seems real.Aliskiren can cause muscle irritation in a small subset of patients. Read more »

HIV protease inhibitors

Could you tell me the spectrum of activity and the mechanism of resistance for the antimicrobial HIV protease inhibitors (Ex: Indinavir)and do they work with gram positve/gram negative bacteria. What bacteria does it work against. Or what sites I...
Eric Daar, M.D.

Response from Eric Daar, M.D.

UCLA School of Medicine
...The HIV protease inhibitor selectively blocks the protease enzyme and prevents an infected cell from producing infectious HIV. Resistance develops when Read more »

Protease Inhibitors with Hep C

I have failed my course of Interfuron therapy. Can you recomend studies going on I could become a part of with Protease inhibitors ??I live in South Florida
Barbara McGovern, M.D.

Response from Barbara McGovern, M.D.

Tufts University School of Medicine
I would go to the website "Clinicaltrials.gov" to find a trial near you. Read more »

what is HIV PROTEASE INHIBITORS.

In taking hydroxyzine pam 25 mg,it states if you are on HIV Protease inhibitors, not to use. What is HIV Protease inhibitors?
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
...HIV protease inhibitors are a family of HIV drugs (such as Kaletra, Viracept, Lexiva, Reyataz) used chronically for the treatment of HIV/AIDS. Read more »
Articles
The Body PRO

Safety and Pharmacokinetic Data for 640385, a New Protease Inhibitor in Development

...Pathogenesis and Treatment, which was held in Paris, France, 1 data were presented about the in vitro anti-HIV activity of a new protease inhibitor (PI) called 640385 (also known as VX-385 or GW0385). This drug, which is being developed by... Read more »
Test Positive Aware Network

The Protease Inhibitor Drugs

...inhibitors are the most complex in terms of pharmacokinetics, drug interactions and dosing changes based on those interactions. Mechanism of Action All protease inhibitors work in the same manner. They block the activity of the protease enzyme... Read more »
Henry J. Kaiser Family Foundation

Protein Accumulation Might Cause Fat Deposits, Other Side Effects in HIV-Positive People Taking Protease Inhibitors, Study Says

...Similarities between genetic conditions that cause early aging and side effects experienced by some HIV-positive people when taking protease inhibitors might explain the fat accumulation associated with the drugs, according to a study published... Read more »
The Body PRO

Double Protease Inhibitor Combinations

...had very good results on combinations which includedritonavir and saquinavir, and patients who had been previously treated withprotease inhibitors, in whom the results were generally disappointing. Abstract I-202. Safety and efficacy of a... Read more »
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lipodystrophy from protease inhibitors

Posted by Anonymous, 4 Replies
...good health. I have accessed all the major medications, plus vitamins to help fight the disease. Once I started taking the new protease inhibitors, I started growing breasts and huge amount of fat in the stomache area...infact, my entire torso... Read more »

bone density loss due to protease inhibitors

Posted by Anonymous, 1 Reply
Curious as to latest info. on research into bone density loss due to HAART therapy. Most research data i've seen goes back to 99 or 2000. Any new data/research into this? Also any info. on clinical trials currently under way looking into this... Read more »

Protease Inhibitors - Hemophilia bleeds

Posted by akcol
Hi, my fiance is a Long Term NonProgressor - 24 years positive, co-infection HCV, with severe Hemophilia A. This is a question for the gentlemen with Hemophilia please. We're requesting any input about any Hemophilic PI increased unusual bleed... Read more »

Hyperglycemia as a result of Protease Inhibitors

Posted by Anonymous
I found a product for reducing glucose levels. It is called Meishan Tea. They make 4 different kinds of tea and I have people that are showing tremendous results on all 4 kinds. However, the people that are presently taking the tea do not have... Read more »