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Protease Inhibitor Viral Load Levels

Here's a taste of what TheBody.com has to offer on this topic:
Get the Facts
The Well Project

Understanding HIV-Related Lab Tests II: Viral Load, Resistance and Tropism

...effective against your virus (andits mutations) In most cases, the genotype is the preferred test. For people who have beenon HIV treatment before and may have HIV that is resistant to a number ofdifferent drugs, including protease inhibitors, the phenotype test may be donein addition to the genotype. When Should You Get a Resistance Test? Resistance testing is recommended for: People who have just become infected with HIV,...
Ask the Experts

Treatment Naive and Viral load roller coaster

Hello,I'm a 44 year old male. Aware of my date of contraction and had acute symptoms that alerted me to the situation. My initial Viral loads were 500-600K but that was still while I was in the acute phase. I immediately enrolled in a trial for...
Eric Daar, M.D.

Response from Eric Daar, M.D.

UCLA School of Medicine
...performed to see whether you have developed resistance to tenofovir and/or FTC, both parts of truvada. Without evidence of protease inhibitor resistance it is unlikely that the problem is the Kaletra or that switching to an alternative PI is the... Read more »

Sustiva/Truvada Viral Load Undetectable but CD4's Not Rising

I have been on the Sustiva Truvada combination for four months. After the first month, my viral load went from 100,000 to undetectable and is still currently at undetectable. My CD4's, however, have remained unbudged at 292. My doctor suggests...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
...then if not improvement on a particular regimen then consider a switch. For some patients better CD4 recovery may be seen on a protease inhibitor based regimen (though your current regimen usually does quite well from the CD4 perspective). KH Read more »

Protease Inhibitors Work for Some Not For Others

Why do some protease inhibitors seem to suppress viral loads to nearly 0in some patients and can not in other patients?
Cal Cohen, M.D., M.S.

Response from Cal Cohen, M.D., M.S.

Harvard Medical School
...experienceare: Noncompliance: the drugs are taken erratically, with missed ordelayed doses Lack of effective combination therapy: the protease inhibitors aretaken in combination with drugs to which resistance has alreadydeveloped. Extensive... Read more »

PROTEASE INHIBITOR TREATMENT

I AM HIV POSITIVE, WITH A CD4 COUNT OF 394 AT LAST READING. MY DOCTOR HAD HAD ME ON 400 MG OF RITANOVIR AND 800 MG OF SAQUINAVIR. HE LATER DECREASED MY DOSAGE TO 200 MG OF RITANOVIR AND 400 MG OF SAQUINAVIR. SINCE THIS DECREASE IN DOSAGE, MY VIRAL...
Cal Cohen, M.D., M.S.

Response from Cal Cohen, M.D., M.S.

Harvard Medical School
...dose, ritonavir is sort of like an expensive form of grapefruitjuice--something to help get the saquinavir levels up.Since your viral load has gone up after you made that dose change, I woulddefinitely be worried about getting inadequate drug... Read more »
Articles
Henry J. Kaiser Family Foundation

Phase II Clinical Trial Shows Vertex's Experimental Protease Inhibitor Lowers Hepatitis C Viral Loads to Undetectable Levels

...release, 2/7). Schering-Plough, Boehringer Ingelheim , Bristol-Myers Squibb and InterMune also are developing experimental protease inhibitors, which have been successful in treating HIV/AIDS, to treat hepatitis C ( New York Times , 2/7). ... Read more »
The Body PRO

Abstract No. 331: Viral Fitness in Patients with Discordant CD4 and Plasma HIV RNA following Protease Inhibitor Failure

...viremia and decrease in CD4 count. A loss of viral fitness significantly correlates with the number of resistant mutations to protease inhibitors, or a loss of viral fitness significantly correlates with the level of phenotypic maximal... Read more »
Gay Men's Health Crisis

Debate Widens Over Protease Inhibitor Side Effects

...protease inhibitor-treated patients. At the 5th Retrovirus Conference last winter, Dr. Cooper reported that 64% of his patients on protease inhibitors showed signs of lipodystrophy (abstract 410). At a late breaker in Geneva, his colleague Andrew... Read more »
Henry J. Kaiser Family Foundation

Protease Inhibitor Lowers Viral Loads Among HIV-Positive People With Drug Resistance, Study Finds

...Tibotec's application for sale and marketing of Prezista for use by HIV-positive people who are resistant to first-line drugs. Protease inhibitors work by blocking the action of an enzyme that cuts HIV proteins into the shorter sections that the... Read more »
Connect With Others

The Failure of Viral Load Tests

Posted by Anonymous, 2 Replies
...bandwagon, using changes in viral load numbers in place of actual health or survival benefits to gain FDA approval of highly toxic protease inhibitors, a primary ingredient of todays HAART. Treatment advocates began using viral load to encourage... Read more »

viral load

Posted by kaliboo, 2 Replies
...I've been trying to find out what your viral load is (approximately, of course) shortly after being infected... and have had no luck... So I guess I'm just wondering... what Read more »

What should I think?

Posted by motherinlaw, 9 Replies
...die and they are not fighting just waiting for the end. When I asked he could give me no specifics...did not know CD4 count or viral load, but said she was down to 75 lbs and was not eating and that her CD4 count had been in single digits (?) She... Read more »

hiv+ Moms w/child

Posted by Anonymous, 1 Reply
Hello, What medication has the dr put you on? How do you feel? Do you take your medication regularly? How much risk is there in having a baby? I like to thank you all for your replys in advance!! Read more »