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Protease Inhibitor Resistance

Here's a taste of what TheBody.com has to offer on this topic:
Ask the Experts

Resistance to protease inhibitors

If you have were infected years ago, before protease inhibitors came out, and you have not yet been on them, is it possible that because of loads of other treatments you are also resistent to them?And, if you have only taken Crixivan with treatment...
Susan Little, M.D.

Response from Susan Little, M.D.

University of California San Diego
...failed it you may have resistance to this drug. There is some degree of cross resistance between Crixivan and some of the other protease inhibitors (especially Ritonavir), so this may be an issue. Drug resistance testing will often help to sort... Read more »

Minor resistance of Protease Inhibitors

I am not on meds but have had a resistance report and told me that I have resistance to IDV... Read more »

Minor resistance to Protease Inhibitors (more details)

I wrote to you yesterday regarding my resistance report although I am not on meds. The report was... Read more »
Articles
San Francisco General Hospital

Protease Inhibitor Resistance and Salvage Therapy

...all patients. If viral replication occurs in the presence of a protease inhibitor, drug-specific resistance emerges. Since the protease inhibitors are structurally similar, viral mutations that confer resistance to one agent are likely to confer... Read more »
The Body PRO

Late Breaker No. LB12: Viral Rebound in the Presence of Indinavir Without Protease Inhibitor Resistance

The observed phenomenon of viral rebound in the absence of resistance to all components of the antiviral regimen was discussed at ICAAC in September, and further described here in Havlir et al's report of 26 patients from ACTG 343. In this study,... Read more »
Henry J. Kaiser Family Foundation

FDA Approves Boehringer Ingelheim's Protease Inhibitor Aptivus to Treat Drug-Resistant HIV

...said Aptivus -- known generically as tipranavir -- will be available at pharmacies nationwide within two weeks (Reuters, 6/23). Protease inhibitors work by blocking the action of an enzyme that cuts HIV proteins into the shorter sections that the... Read more »
Henry J. Kaiser Family Foundation

European Commission Approves Boehringer Ingelheim's Protease Inhibitor Aptivus to Treat Drug-Resistant HIV

...combination with 200 milligrams of Norvir, which is known generically as ritonavir, taken twice daily (Boehringer release , 10/26). Protease inhibitors work by blocking the action of an enzyme that cuts HIV proteins into the shorter sections... Read more »
Connect With Others

lipodystrophy from protease inhibitors

Posted by Anonymous, 4 Replies
...good health. I have accessed all the major medications, plus vitamins to help fight the disease. Once I started taking the new protease inhibitors, I started growing breasts and huge amount of fat in the stomache area...infact, my entire torso... Read more »

bone density loss due to protease inhibitors

Posted by Anonymous, 1 Reply
Curious as to latest info. on research into bone density loss due to HAART therapy. Most research data i've seen goes back to 99 or 2000. Any new data/research into this? Also any info. on clinical trials currently under way looking into this... Read more »

Hyperglycemia as a result of Protease Inhibitors

Posted by Anonymous
I found a product for reducing glucose levels. It is called Meishan Tea. They make 4 different kinds of tea and I have people that are showing tremendous results on all 4 kinds. However, the people that are presently taking the tea do not have... Read more »

Protease Inhibitors - Hemophilia bleeds

Posted by akcol
Hi, my fiance is a Long Term NonProgressor - 24 years positive, co-infection HCV, with severe Hemophilia A. This is a question for the gentlemen with Hemophilia please. We're requesting any input about any Hemophilic PI increased unusual bleed... Read more »