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Protease Inhibitor Drug Interactions

Here's a taste of what has to offer on this topic:
Ask the Experts

Interactions of Protease Inhibitors and Blood Pressure Medications

I was recently placed on Tekturna and HCT to treat my blood pressure, and pravastatin for the P.I. increased cholesterol.Initially, the Tekturna dose of 150mg (the lowest prescription) seemed to create a neuropathy sensation on my left leg and arm. ...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
...I have seen no formal drug interaction studies with protease inhibitors and Aliskiren but the potential for interaction seems real.Aliskiren can cause muscle irritation Read more »

fatigue w/u negative so far

Hi! 44 yo M with AIDS (had a CD4 nadir of 40 in 5/09 along with PCP and MAC) started HAART and last... Read more »


will tahing Viagara cause problems for me, on Trivada, Neviripene? Ta Read more »
AIDS Survival Project

Drug Interactions of Protease Inhibitors and Psychiatric Medications

... Taken from an article by Dan H. Karasic and James W. Dilley Antiretroviral drugs -- especially protease inhibitors -- may interact with medications used to treat mood and anxiety disorders. Protease inhibitors have varying degrees of inhibition Read more »
U.S. Food and Drug Administration

Drugs that May Interact with Protease Inhibitors via CYP3A4 Metabolism -- Table V

...extensively metabolized by CYP3A4. Please refer toNorvir™ product labeling information for further detailsregarding other potential drug interactions via CYP2D6,CYP2C9/19, glucuronidation and other pathways. Drug Category ... Read more »
U.S. Food and Drug Administration

Effects of Protease Inhibitors and Other Commonly Used Medications as Determined by Drug Interaction Studies -- Table IV

... Limited safety and no efficacy data from combination; monitor ALT/AST frequently No evidence of interaction at doses of DLV 400 to 600 mg bid and ritonavir 300 mg bid No safety and efficacy... Read more »
AIDS Project Los Angeles

Drug Interactions Associated with the Protease Inhibitors

... Tips on how to avoid the possibility of drug interactions by thoroughly communicating with your care providers were covered in an article published in the April edition of Positive Read more »
Connect With Others

Thanks for your support and any more advice?

Posted by motherinlaw, 3 Replies
I want to thank everyone for their support and help. I posted this in response to my own previous posting and felt it might have gotten lost in the shuffle and so am reposting. I have just spoken to my son again. He was finally able to convince... Read more »

What should I think?

Posted by motherinlaw, 9 Replies
I will try not to make this too son called yesterday and told me his wife was not doing well. My HIV negative son and three HIV negative grandchildren may soon lose their HIV positive wife and mother. My son and daughter-in-law seem not to... Read more »

ups and downs

Posted by treading_water, 4 Replies
I tested positive a few months ago during a health check for a work visa. My visa was denied and I was left with no job, a plane ticket home, faced with a lot of concerns, and a lot of questions from friends, family , and co-workers as to what... Read more »

Recreational drugs

Posted by Anonymous, 3 Replies
i am going to be starting meds soon and i was wondering what treatments i should avoid. i occasionally do recreational drugs such as ecstasy, ghb, and special k. what kind of reactions can be deadly? i don't want to tell my doctor about my use of... Read more »