Protease Inhibitor Dosages

Here's a taste of what TheBody.com has to offer on this topic:

Get the Facts

Protease Inhibitors in Development

These drugs have not been approved by the Food and Drug Administration (FDA) for use against HIV. Protease Inhibitors These drugs block the protease enzyme. When new viral particles break off from an infected cell, protease cuts long protein strands into the parts needed to assemble a mature virus. When protease is blocked, the new viral particles cannot mature. Protease Inhibitors in Development Several firms are trying to develop a new...

Ask the Experts

PROTEASE INHIBITOR TREATMENT

I AM HIV POSITIVE, WITH A CD4 COUNT OF 394 AT LAST READING. MY DOCTOR HAD HAD ME ON 400 MG OF RITANOVIR AND 800 MG OF SAQUINAVIR. HE LATER DECREASED MY DOSAGE TO 200 MG OF RITANOVIR AND 400 MG OF SAQUINAVIR. SINCE THIS DECREASE IN DOSAGE, MY VIRAL...

Response from Cal Cohen, M.D., M.S.

Harvard Medical School

The usual doses when combining ritonavir and saquinavir are 400 to 600 mg ofritonavir twice daily plus 400 mg of saquinavir. When you use only 200 mg ofritonavir it may be enough to help increase saquinavir levels, but it'scertainly not enough... Read more »

Protease Inhibitors vs. Triple Nucleosides

In late June my doctor gave me the option to change my HIV medication to Trizivir, from Viracept and Combivir. The dosage (two pills a day as opposed to twelve pills a day), was very tempting. I questioned him about the lack of a protease inhibitor...

Response from Cal Cohen, M.D., M.S.

Harvard Medical School

A few comments to see what I can do to clarify what you've read.First - the guidelines. They do comment on some of the protease inhibitors that they recommend as part of a first combination, such as Viracept. They also comment on other... Read more »

garlic/protease inhibitors

someone told me that if you take a protease inhibitor-than you shouldnot take garlic. is this true?...

Response from David Wohl, M.D.

University of North Carolina - Chapel Hill

There are concerns that garlic in sufficient quantities can interfer with certain HIV drugs. This is best described fo rteh protease inhibitor saquinavir (Fortovase, Invirase) but may hold true for other drugs in and outside of this drug class.One... Read more »

New Protease Inhibitor

Hello doc. Are you aware of a new protease inhibitor from Bristol Myers called BMS-232632? It's supposedly more potent than any known protease inhibitor, but I don't have any information on the current phase it's in......

Response from Andrew T. Pavia, M.D.

University of Utah, School of Medicine

BMS-232632 is a new protease inhibitor that is being developed by Bristol Myers Squibb. Luckily, it is about due to get a real name. The studies presented so far have demonstrated that it has a long half life and probably can be used as a once a day... Read more »

Go to Ask the Experts »

Connect With Others

lipodystrophy from protease inhibitors

Posted by Anonymous, 4 Replies

I have known about my HIV+ status now for 6 years, and God has blessed me with continued good health. I have accessed all the major medications, plus vitamins to help fight the disease. Once I started taking the new protease inhibitors, I started... Read more »

bone density loss due to protease inhibitors

Posted by Anonymous, 1 Reply

Curious as to latest info. on research into bone density loss due to HAART therapy. Most research data i've seen goes back to 99 or 2000. Any new data/research into this? Also any info. on clinical trials currently under way looking into this... Read more »

Hyperglycemia as a result of Protease Inhibitors

Posted by Anonymous

I found a product for reducing glucose levels. It is called Meishan Tea. They make 4 different kinds of tea and I have people that are showing tremendous results on all 4 kinds. However, the people that are presently taking the tea do not have AIDS.... Read more »

Protease Inhibitors - Hemophilia bleeds

Posted by akcol

Hi, my fiance is a Long Term NonProgressor - 24 years positive, co-infection HCV, with severe Hemophilia A.

This is a question for the gentlemen with Hemophilia please.
We're requesting any input about any Hemophilic PI increased unusual bleed... Read more »

Connect on Our Bulletin Boards »

Tools

My Health Tracker

Assess Your Risk for HIV

Find Local HIV/AIDS Services

Resource Centers

Guides for People With HIV

View All of Our Guides >>