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Processing Of Gag By Hiv Protease

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AIDS InfoNet

Protease Inhibitors in Development

These drugs have not been approved by the Food and Drug Administration (FDA) for use against HIV. Protease Inhibitors These drugs block the protease enzyme. When new viral particles break off from an infected cell, protease cuts long protein strands into the parts needed to assemble a mature virus. When protease is blocked, the new viral particles cannot mature. Protease Inhibitors in Development Several firms are trying to develop a new...
Ask the Experts

dietary protease vs HIV protease

My mother who is a dietician feels my regimen of Kaletra, Invirase and Truvada is interfering with fat absorption. She feels this is why PI's seem to result in smelly or loose stools. Her solution, dietary enzymes which contain the...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
What you are describing is a combination of enzymes produced by the pancrease to facilitate digestion and absorption of food from the gut. If there is pancreatic insufficiency then those enzymes are given in pill form and that is often helpful. I... Read more »

Protease Supplements?

I'm on Atripla which I believe contains a protease-inhibitor. You can imagine my consternation when I read the entire ingredient label of a supplement I've been taking for 2 years (I did check when I started to make sure there wasn't...
Nelson Vergel, B.S.Ch.E., M.B.A.

Response from Nelson Vergel, B.S.Ch.E., M.B.A.

Program for Wellness Restoration
The Protease product you are taking is an enzyme that the body uses to digest proteins.Atripla has a non nucleoside and two nucleosides, no protease inhibitors.From Wikipedia: Proteases are used throughout an organism for various metabolic... Read more »

Gagging

HISTORY: For 3 years prior to 2000, I had 4 tumors removed which were KS, although I continued to test negative for HIV using 14 different testing methods including some where were still in trials. My oncologist referred me back to infectious...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
If you have not developed any resistance to any HIV meds then perhaps a creative approach to trying easier to take HIV meds (fewer in number and smaller in size) might help. The fact that you tolerated the meds for quite a long time would seem to... Read more »

HIV protease inhibitors

Could you tell me the spectrum of activity and the mechanism of resistance for the antimicrobial HIV protease inhibitors (Ex: Indinavir)and do they work with gram positve/gram negative bacteria. What bacteria does it work against. Or what sites I...
Eric Daar, M.D.

Response from Eric Daar, M.D.

UCLA School of Medicine
The HIV protease inhibitor selectively blocks the protease enzyme and prevents an infected cell from producing infectious HIV. Resistance develops when mutations emerge in the viral protease enzyme that prevent the inhibitor from interacting with... Read more »
Connect With Others

lipodystrophy from protease inhibitors

Posted by Anonymous, 4 Replies
I have known about my HIV+ status now for 6 years, and God has blessed me with continued good health. I have accessed all the major medications, plus vitamins to help fight the disease. Once I started taking the new protease inhibitors, I started... Read more »

Abbott pharmaceuticals price gouging protease inh

Posted by BabyPeanut
Editorial, The Center for AIDS (12/15/03)

In a move that startled healthcare professionals and community members alike, Abbott pharmaceuticals announced a price increase of almost 500% for its protease inhibitor ritonavir (Norvir). Norvir is widely... Read more »

Protease Inhibitors - Hemophilia bleeds

Posted by akcol
Hi, my fiance is a Long Term NonProgressor - 24 years positive, co-infection HCV, with severe Hemophilia A.

This is a question for the gentlemen with Hemophilia please.
We're requesting any input about any Hemophilic PI increased unusual bleed... Read more »

Process of elimination

Posted by Anonymous, 1 Reply
Had a low risk exposure sept/oct last year unprotected vaginal insertive. Went for a full medical last week and just got results of blood test/liver function/kidney function and they were all fine, as was my blood pressure etc. My question is this.... Read more »

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