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Prezista And Combivir Combination

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An Overview of Prezista (Darunavir, TMC114)

dar-UE-na-vir Brand Name: Prezista Other Name(s): TMC 114, TMC114 Drug Class: Protease Inhibitors Patient Information PREZISTA (pre-ZIS-ta) Darunavir Read this Patient Information before you start taking PREZISTA and each time you get a refill. There may be new information.This information does not take the place of talking to your doctor or healthcare provider about your medical condition or your treatment. What is...
Ask the Experts

Improved Triglycerides with Prezista/Norvir Combination?

I am on a treatment which includes 4x 100mg Norvir daily. It has been suggested that I add Prezista to my treatment in order to reduce the amount of Norvir, thus getting better control over my triglycerides. I can't find information to...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
Thank you for your post.It sounds like you must be taking a tipranavir-based regimen-- a switch to darunavir (Prezista)/ritonavir (if permitted by your drug resistance pattern) may lower your triglycerides. In a study versus Kaletra... Read more »

Combination to use after EFV + Combivir combo

Hi,I'm using a Sustiva + Combivir combo fairly well for 4 1/2 yrs with viral load undetectable at all times and 100% adherence. I have been on other combinations in the past but never experienced virologic failure. I have had hepatitis A and...
Eric Daar, M.D.

Response from Eric Daar, M.D.

UCLA School of Medicine
It sounds like you are doing great on your current regimen with the potential exception of lipoatrophy which may be associated with the NRTIs. I suspect viral rebound will not occur if you continue to take your medication consistently. However, if... Read more »

Combivir and Viramune Combination - Time for a Switch?

Dear Dr:I have been positive since February 2003. My CD4 is 708 and my viral load has been undetectable since December 2003. I have been taking Combivir and Viramune since April 2003 with no problems except some fatigue. I am concerned about facial...
Eric Daar, M.D.

Response from Eric Daar, M.D.

UCLA School of Medicine
Thank you for your post.It sounds like you have done fantastic on therapy with excellent viral suppression and high CD4 cells. To answer your question I would need to know whether you are developing facial lipoatrophy and/or neuropathy or are simply... Read more »

Paxil / Combivir / Viracept - and Bad Reactions from this combination?

I am currently taking Paxil (just started). I am also an alcoholic (heavy drinking for 10 years, not drinking now) and HIV+ for 12 years. Doctor wants me to start on Combivir and Viracept. Could I still continue with the Paxil along with these?...
Andrew T. Pavia, M.D.

Response from Andrew T. Pavia, M.D.

University of Utah, School of Medicine
Paxil, like many antidepressants is metabolized in the liver by a series of enzymes called the cytochrome P450 system. All of the protease inhibitors have some effect on this system, decreasing the rate of breakdown of some drugs, but it varies... Read more »
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Splitting Prezista 600mg into thirds...

Posted by lovelife, 2 Replies
I need to take Prezista 800mg. If I have only Prezista 600mg, can I brake the pill into thirds so I can take one 600mg and then add 200mg more from the splitting?
Is this feasible? Safe? Read more »

Prezista - New PI designed for Resistant Virus

Posted by Survivor, 2 Replies
WASHINGTON, June 23 (Reuters) - U.S. health officials on Friday approved the use of a new HIV drug, made by Johnson & Johnson <JNJ.N>, in combination with related therapies to help treat patients who do not first improve with other... Read more »

Reyataz and Combivir

Posted by Anonymous
Just was wondering if anyone else is taking this combination. I just re-started therapy after a 12 month holiday. Please let me know what you have experienced. I am new here and any info would be greatly appreciated.
Thanks, David

Read more »

Switching from Combivir to Truvada???

Posted by Anonymous, 4 Replies
I started Combivir/Sustiva a year ago. I've had great results. VL undetected. My doctor is suggesting the switch from Combivir/Sustiva to Truvada/Sustiva. Has anyone made the switch. What are the benefits aside from the once a day regimen. Any side... Read more »

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