Post Exposure Prophylaxis Dosing

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Treatment After Exposure to HIV

For serious exposures, the U.S. Public Health Service recommends using a combination of three approved ARVs for four weeks. For less serious exposure, the guidelines recommend four weeks of treatment with two drugs: zidovudine (Retrovir, AZT) and lamivudine (Epivir, 3TC). In January 2001, the Centers for Disease Control warned against using nevirapine (Viramune) for PEP because of the risk of liver damage. See Fact Sheet 431 for more...

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Post-Exposure Prophylaxis, Occupational Exposure

Hi Dr Frascino, I am a medical resident and today suffered an occupational injury from an AIDS patient. I was placing a 20G IV when the patient jumped and it stuck my finger. The injury wasn't very deep, but I had a bit of blood from the...

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation

Hi,Yes, PEP further reduces your HIV-acquisition risk; however, we can't say by exactly how much because there are many confounding variables, including viral strain, viral load, whether the source patient was on antiretrovirals, time to your... Read more »

Does Post Exposure Prophylaxis increase the odds of a false negative test 30 days after exposure?

Hi, Dr. Bob. I hope my question has not already been answered. I will try to make it quick. A month ago I was raped by a man I do not know. Immediately after, I called the police and was taken to the ER where they prescribed me 30 days of PEP (and...

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation

Hi.Sorry to hear about the sexual assault. I hope the perpetrator is now behind bars.The guidelines for post-PEP HIV testing recommend HIV-antibody testing at four to six weeks, three months and six months from the date of exposure.Dr. Bob... Read more »

What should I expect from post exposure prophylaxis (PEP) medication?

Hi everyone, I'm very new to this so please bare with me. As yet I've not had a positive test, but I have had a possible exposure to the the hiv virus.I've acted quickly and my doctor has prescribed post exposure prophylaxis...

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation

Hello,I'm glad you acted quickly following your HIV exposure. And assuming that exposure was significant, I'm also glad your doctor prescribed PEP. However, I'm not so glad that he didn't tell you what to expect or answer your... Read more »

Post Exposure Prophylaxis (PEP) for 19 y/o male

Hi, I'm a 19 y/o gay male. I had unprotected receptive anal intercourse with a man that I had known for almost two weeks. The person states as of January of 2008 he was negative. I don't know what to believe. The encounter was in the...

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation

Hello,You had an unprotected anal receptive encounter with a guy of unknown HIV status (who told you he was negative as of January 2008) and you have no idea "if his bodily exchange fluid and passed." And for this your doctor gave you... Read more »

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Post-Exposure Prophylaxis (PEP) - Help

Posted by MF2010

Hi all,

I've been exposed to HIV in the beginning of this month.
My condom completely broke and i had sex for a couple of minutes completely exposed. I suspect my partner was HIV infected.

Went straight to the hospital and started Post-Exposure... Read more »

exposure 10 days ago--prophylaxis drug an option?

Posted by Anonymous, 2 Replies

I'm happily married and monogamous for the past 10 years. Ten days ago 5 minutes of drunken stupidity could have changed all that.

I had gone to a strip club (which is a rarity for me). I got way too drunk and stupid, and got a lap dance. The... Read more »