Physical Properties Of Stavudine

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Stavudine (Zerit)

What Is Stavudine? Stavudine (Zerit) is a drug used as part of antiretroviral therapy (ART). It is manufactured by Bristol-Myers Squibb. The original patent on stavudine has expired. The U.S. Food and Drug Administration (FDA) approved generic forms of stavudine for sale in the U.S. and under PEPFAR (see Fact Sheet 475 ). Stavudine is also known as d4T or didehydro-deoxythymidine. Stavudine is the most commonly used anti-HIV medication...

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PHYSICAL APPEARENCE CHANGE

I'm a newbe,and I'm worried about physical changes in my appearence,I am scared that my stomache will bloat,my shoulder blades will pretrude,and my muscle will deteriate.Im on comb/sustiva,and wonder if there is any combo's studied...

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES

Thanks for your question.A key concept that is often underappreciated is that we don't fully understand what the causes of these body shape changes are. It is clear from several studies that long-standing, or severe HIV disease places one at... Read more »

Can I take Zerit (Stavudine, d4T) with Viread (Tenofovir).

Hi, I just had a quick question. I've been researching everywhere but couldnt find an answer, if I'm taking Zerit (Stavudine, d4T) and Sustiva (Efavirenz, Stocrin), can I take Viread (Tenofovir).Thanks so much for all your help. God bless. ...

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES

Hello and thank you for your post.While d4T (Zerit) is not routinely used with tenofovir (Viread, Truvada),nor is this a commonly used NRTI backbone to be taken with efavirenz, there's no particular reason why the two drugs couldn't be... Read more »

Forgot dose of stavudine (2 hours)

I forgot to take my stavudine dose on time and I ended up taking it 2 hours later. What is the probability of this causing resistance? Is there a window of time to take the missed dose that is relatively safe? Thank you....

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine

Should not be a problem. KH... Read more »

resistance to stavudine

Is there any data that explains why some patients experience clinical failure on a regimen containing stavudine if there are no clinically observed codon mutations linked to stavudine resistance?...

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine

Good question and hard to get an answer. A couple of points though. Although we can't seem to find the mutation we believe causes d4T resistance in the test tube in people, we see the cases you describe. This may be related to other mutations... Read more »

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Posted by Anonymous, 3 Replies

I recently had a routine physical. My doctor did a finger prick to check my hemoglobin. If I were HIV+ would it show up in something like this? Thanks

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Depleted emmotionally and physically!!!

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I am the "It's all over folks" poster on page 5 of this forum if you want more background information.

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As A Survivor of Childhood Physical & Sexual Abuse

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Physical symptoms keep coming back?

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So I've been infected for about a month now. I started getting symptoms after week one and after week 2 I found out I was positive. After about 7-8 days of symptoms, I started feeling a lot better physically. I even had my appetite back and... Read more »

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