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Non-nucleoside Reverse Transcriptase Inhibitors Stop Hiv Production By Binding To

Here's a taste of what TheBody.com has to offer on this topic:
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AIDS InfoNet

Non-Nucleoside Reverse Transcriptase Inhibitors in Development

... Non-Nucleoside Reverse Transcriptase Inhibitors NNRTIs in Development NNRTIs No Longer in Development Note: Several fact sheets describe drugs that are being tested against HIV: Fact Sheet 410 : nucleoside analog reverse transcriptase inhibitors (nukes) Fact
Ask the Experts

Psycological response to longterm HIV diagnosis?

I read a most interesting and self confirming article in the May/June Issue of PA (Positively Aware) magazine. It was titled, "Is it all in your head?" Since I have been diagnosed now being over 16 years, I have been finding myself depressed, mood...
Robert J. Frascino, M.D.

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation
...quite well.Some drugs float more or less freely in the blood while others bind to proteins. Compared with nucleoside/ nucleotide reverse transcriptase inhibitors (NRTIs) and non-nucleoside reverse transcriptase inhibitors (NNRTIs), protease... Read more »

Reverse transcriptase inhibitors effect on telomeres

I recently started on Atripla and was trying to understand how it works and potential long term effects. So as I understand it (and I'm not a microbiologist by any stretch) the main purpose of the Sustiva in Atripla is to inhibit the reverse...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
...I am not aware of any data that has shown that nucleoside reverse transcriptase inhibitors (that are HIV DNA chain terminators not directly involving human DNA) clinically impact human chromosome or telomore length/function. Read more »

Stepped on a Needle on A Beach and Get Infected

Dear Dr. Bob,I am 64, married, and have been positive for over 14 years. I was infected in a most bizarre fashion....I stepped on a hypo needle on a Florida beach. I started on Crixivan and Combivir 13 years ago, and am still on them. CD4 is 1300...
Robert J. Frascino, M.D.

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation
...Hi,Contracting HIV from stepping on a discarded hypodermic needle is indeed a very rare occurrence. With your normal CD4 count and undetectable Read more »

CNS penetration of Atripla/Ziagen/Isentress

AIDS patients need CNS penetrating anti-vral drugs, right Dr.? In order to bettter fight dementia, memory loss, etc., right? so, how do isentress, Ziagen and 3-in-1 Atripla stack up? Thanz!
Robert J. Frascino, M.D.

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation
...quite well.Some drugs float more or less freely in the blood while others bind to proteins. Compared with nucleoside/ nucleotide reverse transcriptase inhibitors (NRTIs) and non-nucleoside reverse transcriptase inhibitors (NNRTIs), protease... Read more »
Articles
AIDS InfoNet

Nucleoside Analog Reverse Transcriptase Inhibitors in Development

... Nucleoside Analog Reverse Transcriptase Inhibitors Nucleoside Analogs (Nukes) in Development Nukes No Longer in Development NOTE: Several fact sheets describe drugs that Read more »
The Body PRO

Clinical Trials of HIV-1 Reverse Transcriptase Inhibitors

... Long-Term Virologic and Immune Responses in Subjects Maintained on Exclusive Nucleoside Analog (NRTI)-Based Therapy in ACTG 364 (Poster 322) Authored by M. Albrecht, S. Hammer, S. Liou, R. Bosch, and D. Katzenstein Read more »
The Body PRO

Pharmacokinetics of MKC-422, One of the Next Non-nucleoside Reverse Transcriptase Inhibitors, Together with ZDV, 3TC, d4T, and ddI

...MKC-442 is a non-nucleoside reverse transcriptase inhibitor with potent activity in early phase I/II studies. Prior to moving forward with larger trials testing the drug's activity, this Read more »
U.S. Centers for Disease Control and Prevention

United Kingdom: "Virological and Immunological Outcomes at 3 Years After Starting Antiretroviral Therapy with Regimens Containing Non-Nucleoside Reverse Transcriptase Inhibitor, Protease Inhibitor, or Both in INITIO: Open-Label Randomized Trial"

...-- a large international randomized trial -- the study authors compared antiretroviral therapy with two nucleoside analogue reverse transcriptase inhibitors (didanosine + stavudine) plus either a non-nucleoside reverse transcriptase inhibitor... Read more »
Connect With Others

Lab, med change, confusion

Posted by kaplan08, 2 Replies
Labs of last year have shown a vload range between <400 and 793, with <400 being most recent; CD4 percentage range from 31% to 34%, with 33% being most recent. Taking only Viramune and Combivir -a test has recently shown resistance to... Read more »

DDC Bites the Dust

Posted by Bear60, 1 Reply
...Pharmaceuticals announced that it will be ending the sale and distribution of Hivid (zalcitabine, also known as ddC), a nucleoside reverse transcriptase inhibitor (NRTI) originally approved in 1992. The tablets will not be available in U.S.... Read more »

Vasculitis and HIV

Posted by Anonymous, 3 Replies
...Does anyone know about vasculitis and HIV? Read more »

What should I think?

Posted by motherinlaw, 9 Replies
...I will try not to make this too long...my son called yesterday and told me his wife was not doing well. My HIV negative son and three HIV negative grandchildren may soon lose their HIV positive wife and mother. My son and daughter-in-law Read more »