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Neuropathy And Capsaicin

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Test Positive Aware Network

Capsaicin Patch for Neuropathy Granted FDA Review

NeurogesX, Inc., a biopharmaceutical company focused on developing and commercializing novel pain management therapies, announced on November 14 that the Food and Drug Administration (FDA) has accepted for review the company's supplemental new... Read more »
HIV i-Base

FDA Rejects Capsaicin Patch for HIV-Related Neuropathy

On 9 February the Advisory Committee to the US FDA rejected by a vote of 12-0 an application for a capsaicin skin patch (NGX- 4010, Qutenza) for an indication of HIV-related pain based on proven efficacy. They also voted 11-0 that data the benefits... Read more »
U.S. Centers for Disease Control and Prevention

Controlled Trial of High-Concentration Capsaicin Patch for Treatment of Painful HIV Neuropathy

There are limited effective treatments for the painful condition HIV-associated distal sensory polyneuropathy (HIV-DSP). Capsaicin desensitizes cutaneous nociceptors resulting in reduced pain. The authors reported on a placebo-controlled study of a... Read more »
Ask the Experts

Spinal Neuropathy Treatment

What are the current treatment regimens. I have beeen using neurontin, but it is only partially effectuve. Due to a spinal cord infection which caused paraplegia I have sensory neuropathy in the buttocks area which results in unbearable pain if I...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
There are a number of new or investigational treatment options for neuropathy. Cymbalta is helpful in some patients. Prospaptide O and high strength capsaicin are under study for peripheral neuropathy. I often seek consultation from paain... Read more »

Neuropathy

Hello Dr. HenryI have had difficulty with neuropathy in my feet for a few years. We have tried to not use d4t and ddi. However, I think the pain may be here to stay. I have tried neurotin. But, it seems no matter what dose it didn't help. So, I...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
Amitryptiline, Cymbalta, topical lidocaine or capsaicin,N-acetyl carnitine, acupuncture, pain clinic referral--all can unpredictably be helpful in differnet patients. KH... Read more »

neuropathy in feet

ive recently had worse pain in feet (no d meds) & tried amiltryptiline, neurontin without success, now on morphine & effexor (my psy says that effexor also works for physical pain; do u know something about this?thksps:everyone can respond...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
3TC can also aggravate neuropathy in some patients. There are several clinical trials looking at new drugs for neuropathy. One is using a potent form of capsaicin that is painted on the involved area. The ACTG is also about to open a study using a... Read more »

Voltaren Cream for Peripheral Neuropathy

I have very painful peripheral neuropathy. I have been on many antiretrovirals for about 10 years (including the usual suspects (DDI, D4T, dapsone to name only a few PN meds). I am adequately VL suppressed on D4t, 3TC, Fortavase and Ritonavir. I...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
Greg,I have not used Voltaren cream for anything (there is a solution available here for use in the eyes) so I can't be too helpful. Capsaicin cream can be of some use for peripheral neuropathy. Substituting off the D4T to something like... Read more »
Connect With Others

Neuropathy?

Posted by Anonymous, 1 Reply
Is it possible to have hiv neuropathy (not the neuropathy produced by med but by hiv itself) soon after being infected, that its withing the first year of being infected? How likeky?

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Neuropathy?

Posted by Anonymous
Is it possible to have hiv neuropathy (not the neuropathy produced by med but by hiv itself) soon after being infected, that its withing the first year of being infected? How likeky?





Read more »

What is neuropathy pain?

Posted by bura, 3 Replies
Can someone describe what is neuropathy pain? Read more »

NEUROPATHY

Posted by Anonymous, 1 Reply
i am experiencing what i think is the beginnings of hiv neuropathy. in the mornings, i can see the blood fill my lower legs and standing becomes uncomfortable. standing anywhere for long periods of times becomes uncomfortable. my legs are weak. ... Read more »