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Natural Protease Inhibitors

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Get the Facts
AIDS InfoNet

Protease Inhibitors in Development

... Protease Inhibitors Protease Inhibitors in Development PIs No Longer in Development NOTE: Several fact sheets describe drugs that are being tested against HIV: Fact Sheet 410 : nucleoside analog reverse transcriptase inhibitors (nukes)
Ask the Experts

Protease Inhibitors with Hep C

I have failed my course of Interfuron therapy. Can you recomend studies going on I could become a part of with Protease inhibitors ??I live in South Florida
Barbara McGovern, M.D.

Response from Barbara McGovern, M.D.

Tufts University School of Medicine
I would go to the website "Clinicaltrials.gov" to find a trial near you. Read more »

Protease Inhibitors... Cause Bone Loss???

Hi... I'm currently taking Reyataz and I just read something about Protease Inhibitors and bone loss... Do they cause bone loss? I already have osteoperosis and have suffered awful compression fractures down my spine and DO NOT need any more of...
Sharon Lee, M.D.

Response from Sharon Lee, M.D.

University of Kansas Medical Center
...important to get accurate info. SOme of the PI's may increase the rate of bone loss, although there are differences among the protease inhibitors (different side effects and different intensities of the side effects). Epivir and Zerit are in the... Read more »

Protease Inhibitors and Elevated Cholesterol & Triglycerides

I have been in 'drug failure' until taking a PI regimen consisting of ABT-378, Amprenavir, Crixivan & Combivir. Since starting this protocol last March, I have now undetectable levels of HIV for the first time since diagnosed with AIDS in 1992,...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
Wow -- what a story! I agree that your current regimen is doing very good job from HIV perspective and that the high levels of the PIs achieved with use of ritonavir is key to that but also a likely culprit for the high lipids. Use of fenofibrate... Read more »

what is HIV PROTEASE INHIBITORS.

In taking hydroxyzine pam 25 mg,it states if you are on HIV Protease inhibitors, not to use. What is HIV Protease inhibitors?
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
...HIV protease inhibitors are a family of HIV drugs (such as Kaletra, Viracept, Lexiva, Reyataz) used chronically for the treatment of HIV/AIDS. Read more »
Articles
Gay Men's Health Crisis

Debate Widens Over Protease Inhibitor Side Effects

...protease inhibitor-treated patients. At the 5th Retrovirus Conference last winter, Dr. Cooper reported that 64% of his patients on protease inhibitors showed signs of lipodystrophy (abstract 410). At a late breaker in Geneva, his colleague Andrew... Read more »
U.S. Centers for Disease Control and Prevention

United Kingdom: "Virological and Immunological Outcomes at 3 Years After Starting Antiretroviral Therapy with Regimens Containing Non-Nucleoside Reverse Transcriptase Inhibitor, Protease Inhibitor, or Both in INITIO: Open-Label Randomized Trial"

...transcriptase inhibitors (didanosine + stavudine) plus either a non-nucleoside reverse transcriptase inhibitor (efavirenz, EFV) or a protease inhibitor (nelfinavir, NFV), or both (EFV/NFV) in HIV-1-infected patients who had not previously... Read more »
San Francisco General Hospital

Prophylaxis of OIs in the Age of Protease Inhibitors

...antiretroviral agent of sufficient potency to suppress viral reproduction and allow the immune system to rebound. Enter the protease inhibitors! As concerned clinicians are aware, these agents have produced the most profound viral load reductions... Read more »
San Francisco General Hospital

Prophylaxis of OIs in the Age of Protease Inhibitors -- an Update

...for AIDS- associated opportunistic infections have both decreased dramatically in the United States since the advent of the protease inhibitors ( Figure ). In most of the cohorts studied to date, the rates of new cases of PCP, disseminated MAC,... Read more »
Connect With Others

lipodystrophy from protease inhibitors

Posted by Anonymous, 4 Replies
...good health. I have accessed all the major medications, plus vitamins to help fight the disease. Once I started taking the new protease inhibitors, I started growing breasts and huge amount of fat in the stomache area...infact, my entire torso... Read more »

bone density loss due to protease inhibitors

Posted by Anonymous, 1 Reply
Curious as to latest info. on research into bone density loss due to HAART therapy. Most research data i've seen goes back to 99 or 2000. Any new data/research into this? Also any info. on clinical trials currently under way looking into this... Read more »

Protease Inhibitors - Hemophilia bleeds

Posted by akcol
Hi, my fiance is a Long Term NonProgressor - 24 years positive, co-infection HCV, with severe Hemophilia A. This is a question for the gentlemen with Hemophilia please. We're requesting any input about any Hemophilic PI increased unusual bleed... Read more »

Hyperglycemia as a result of Protease Inhibitors

Posted by Anonymous
I found a product for reducing glucose levels. It is called Meishan Tea. They make 4 different kinds of tea and I have people that are showing tremendous results on all 4 kinds. However, the people that are presently taking the tea do not have... Read more »