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Muscle Wasting Syndrome

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AIDS InfoNet

Wasting Syndrome

Hormone levels can affect the metabolism. HIV seems to change some hormone levels including testosterone and thyroid. Also, cytokines play a role in wasting. Cytokines are proteins that produce inflammation to help the body fight infections. People with HIV have very high levels of cytokines. This makes the body produce more fats and sugars, but less protein. Unfortunately, these factors can work together to create a "downward spiral." For...
Ask the Experts

Wasting Syndrome - sunken face

Why do I and some other people with AIDS have no trouble putting on muscle, but have not an ounce of fat? I have a fabulously well muscled body with not an ounce of fat. Which looks fine but when you look at my face you can see that there is muscle...
Cal Cohen, M.D., M.S.

Response from Cal Cohen, M.D., M.S.

Harvard Medical School
Michael,... Read more »

Prevalence of AIDS-associated muscle wasting

I am trying to assess the prevalence of AIDS-associated muscle wasting in the United States. Any information regarding the number of patients suffering from wasting symptoms or methods of estimating this population would be greatly appreciated. I...
Alvan Fisher, M.D.

Response from Alvan Fisher, M.D.

Brown University School of Medicine
Everything has changed in the last few years since the advent of HAART. Prior to this (1980s-mid90s) we saw lots of cases of AIDS assoc wasting...indeed most who died from AIDS had evidence of wasting. Studies done then clearly indicated a... Read more »

fatigue, muscle & bone pain, wasting

Hello;I am a nurse, and am on Combivir & Norvir. Dx in 1990.Weight then about 200 I am 6'4". Now 167. 42 year old white male, Dx with cervical stenosis and had 2 lumbar surg at L4-L5 bilaterally. Osteo of course severe carpal tunnel...
Robert J. Frascino, M.D.

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation
Hi,First, the good news is that your HIV infection seems to be well controlled on your current regimen: CD4 count of 902 and a non-detectable viral load. I'm amazed you've tolerated Norvir all this time. It's not the most... Read more »

Muscle wasting

I cant tell you how much I love this web site. My problem is of course the fat thing(3tc, sustivia, and abacavir), viral load undetectable, cd4 250.My main problem is trying to figure out whats going on with my muscles. Ive been to a neurologist...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
Thanks for your comments.Based on what you describe, the first question that I have is whether the facial thinning that you have is due to fat or muscle atrophy.In the case of the later, it would be important to make sure that one is not dealing... Read more »
Connect With Others

Wasting severly--HELP

Posted by Anonymous, 3 Replies
My loved one is wasting away, how much weight can a person lose and still get healthier? I am very scared and worried about him. Read more »

Wasting---help me

Posted by Anonymous, 4 Replies
I'm sorry to come on board, but I need help. My husband is wasting away. He's newly on meds, but not gaining. It seems as though his buttcheeks are completely gone. I don't know what to do.

I'm afraid. He's down to 120 and losing despite putting... Read more »


Posted by Anonymous, 4 Replies
i am worried that my muscles are going to the next thing to go.i have almost no body fat left, and with the anemia, just about no energy to get any exercise. i eat like a pig,and still i continue to lose weight. any advice?

Read more »

muscle & joint pain

Posted by ElGringo, 1 Reply
Just wondering if anyone else has probs with joint disease or muscle wasting? I didn't have much of an issue til about 3 yrs ago & the cartilidge in my joints started withering away. Did the usual xrays etc & short of joint replacement, only... Read more »