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Read Now: Expert Opinions on HIV Cure Research

Monthly Increase Of Cd4 On Atripla

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Get the Facts
AIDS InfoNet

CD4 Cell Tests

What Are CD4 Cells? Why Are CD4 Cells Important in HIV? What Is a CD4 Test? What Factors Influence a CD4 Cell Count? How Are the Test Results Reported? What Do the Numbers Mean? Ongoing Monitoring "Non-AIDS" Illness and Death The Bottom Line What Are CD4 Cells? CD4 cells are a type of lymphocyte (white blood cell). They are an important part of the immune system. CD4 cells are sometimes called T-cells. There are two main types of...
Ask the Experts

CD4 Count V. CD4% Count (ABSOLUTE CD4 COUNT VERSUS CD4%, 2010) (WHEN TO START TREATMENT, 2010)

Hi,I was diagnosed with HIV around 15 months ago. Since then my health has been good (especially in the last six months) but my CD4 count has fallen a bit rapidly from 470 to 371 to 324 over this time period. However, my CD4 percentage count has...
Robert J. Frascino, M.D.

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation
Hello,You are correct: The CD4% is generally considered the more accurate indicator of immune integrity, as it doesn't tend to fluctuate as much due to intercurrent illnesses and other non-HIV-related factors. (See below.)Regarding beginning... Read more »

Why CD4 goes down while CD4% goes up (ABSOLUTE CD4 COUNT VERSUS CD4%, 2009)

Hi Dr. Bob, it is a real pleasure to read your answers full of help, professionalism, generosity and fun. I started therapy at an absolute CD4 of 405 and 26% and VL above 100k, I started Atripla six months ago after the first three months my CD4...
Robert J. Frascino, M.D.

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation
Hi,When it comes to monitoring HIV disease, it's important to look for long-term trends rather than worry about transient swings, especially in absolute CD4 counts. Absolute CD4 counts are calculated from the absolute lymphocyte counts. The... Read more »

Undetectable Viral Load but CD4 is still decreasing, can you help? (DISCORDANT RESPONSE TO ANTIRETROVIRAL THERAPY, 2011) (CD4 COUNTS NOT INCREASING DESPITE UNDETECTABLE VIRAL LOAD, 2011)

Hi Dr Bob, can you help? My partner has been taking Atripla since december and for the last couple of months has had a undectable viral load, two months a go his CD4 count was 120, then since then it has been dropping and yesterday was told it was...
Robert J. Frascino, M.D.

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation
Hello,Your partner is experiencing a discordant response to his antiretroviral regimen (Atripla). His virologic response is excellent, as his HIV plasma viral load is undetectable. However, his immunological response remains poor, as his CD4 count... Read more »

CD Count. (CD4 COUNTS NOT INCREASING DESPITE UNDETECTABLE VIRAL LOAD, 2010) (LACK OF CD4 RESPONSE DESPITE TREATMENT, 2010)

Since my last consultation 6 months ago my CD4 count has gone up 2 only points from 153 to 155.I got this new result yesturday. My last increase was almost 50 points in 6 months. How concerned should I be about such a slow and disappointing...
Robert J. Frascino, M.D.

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation
Hi,The problem of poor CD4 response despite use of effective antiretroviral therapy that drives the HIV plasma viral load to undetectable levels is a vexing and perplexing problem. We still don't completely understand the reason for this... Read more »
Connect With Others

New Diagnosis Started Atripla- What is the expected rise in CD4 count?

Posted by live_life80, 4 Replies
Hey everyone,

I am new to the boards and being HIV positive. I will tell you a little bit about myself. I am a 25 year old gay male and was infected about 9 months ago and diagnosed 3 months ago. I feel lucky that I caught it so soon, but it has been... Read more »

How to increase CD4 Count?

Posted by Just_Joe, 2 Replies
I have had HIV since November 2008 and 3-4 months later am undetectable with CD4 Count in the 200's but my last CD4 count in January 2010 is in the 300's. My doc said my ratio looks good as far as my CD4 count goes and just keep taking my meds, will... Read more »

Increasing CD4 count

Posted by notinterested, 4 Replies
Hello everyone,
I usually come on here and offer support and advice, and now I'm looking for some. I got my labs back and for the second time in a row by CD4 dropped. I've chosen not to know the number but from pestering my partner and getting hints,... Read more »

IL-2 Induces Sustained CD4 Cell Increases

Posted by Anonymous, 1 Reply
IL-2 Induces Sustained CD4 Cell Increases in HIV-Infected Patients


By Deborah Mitchell

TORONTO, Sep 20 (Reuters Health) - The addition of recombinant interleukin-2 (IL-2) to an HIV antiretroviral therapy produces an increase in CD4+ T-cell counts,... Read more »