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Mitochondrial Toxicity Symptoms

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Mitochondrial Toxicity

Lactic acidosis can be fatal. See your health care provider immediately if you have these symptoms. MT may also cause nerve damage (peripheral neuropathy, see Fact Sheet 555 ). It has been linked to kidney damage and hearing loss. Some researchers believe it might also contribute to fat redistribution (lipodystrophy, see Fact Sheet 553 ) in people taking antiretroviral medications (ARVs). How Do ARVs Cause MT? Mitochondria have an enzyme...
Ask the Experts

What can I do to prevent mitochondrial toxicity?

Nelson: I am taking Zerit+Kaletra+Epivir and am very aafraid of this thing I keep hearing about called mitochondrial toxicity. What are the symptoms and what supplements or things can I take to prevent it? I want to get off Zerit but my doctor does...
Nelson Vergel, B.S.Ch.E., M.B.A.

Response from Nelson Vergel, B.S.Ch.E., M.B.A.

Program for Wellness Restoration
I wish there was a clear answer to your question. As you probably remember from your biology class in school, the mitocondria are tiny cells within a cell that produce energy as ATP from sugars and fats. It seems that nucleoside analogs (NRTIs) not... Read more »

thank you ! thank you!!! (Mitochondrial toxicity)

Thank you for your responses about mitochondrial toxcity and nukes.You have been so informative.I think alot of doctors don't take the time to explain in depth to their patients,because they think details may go over their heads,but I'm...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
Thanks for your warm comments.As you point out, the only accurate test for mitochondrial injury currently is a lactic acid level. The test is promblematic (difficult to do reliably) and probably only picks up late injury.There are several groups... Read more »

How is Mitochondrial Toxicity Ruled Out?

Dear Dr. Bob,I have been HIV+ for 17 years, and on Viracept, D4T, 3TC for the past three years. My viral load undetectable, CD4's averaging 900, but I have had severe fatigue for around 9 months. I am often so exhausted that I am afraid of...
Robert J. Frascino, M.D.

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation
Hello Whipped in S.F.,Well, Ill stand by my previous statement, "we have much to learn about how to diagnose and treat mitochondrial toxicity." Is there a way to "conclusively rule it out?" Well, there are ways, but these types... Read more »

Carnitine and Riboflavin to combat mitochondrial toxicity

Are you using carnitine and riboflavin routinely to try to overcome the possible mitochondrial toxicity that hypothetically may contribute to lipodystrophy? If so, what doses of each are you using?...
Alvan Fisher, M.D.

Response from Alvan Fisher, M.D.

Brown University School of Medicine
No, not routinely.Alvan Fisher, M.D.... Read more »
Connect With Others

Toxicity: Your Experiences

Posted by Anonymous
Ok.

I recently tested positive and even though my viral load under 2,000 i have a 389 CD4.

I have been investigating epivir/ziagen and viread..they might be available in a new study on a once daily dosing schedule.

My question is, what do u think about... Read more »

Is gay culture toxic?

Posted by Anonymous, 3 Replies
Everywhere you turn you see images of young, clean shaven, hairless, "buffed" boys gracing the gay mags and movies. Who actually looks like most of these people? All we are given to watch on tv is Will and Grace. They represent like 5% of the entire... Read more »

A Toxic Combination

Posted by Choosing2Liv, 9 Replies
If my dilemma was:

- just dealing with the virus; or

- just suffering with the guilt of cheating on my wife; or

- just the feelings of rejections by those who said they loved me; or

- just the constant blaming, belittlement and bursts of rage from my... Read more »

Symptoms Symptoms Symptoms!!!

Posted by plantation84, 1 Reply
Hey Everyone,

Ok where to start... I stood on a needle on holiday 2 months and 13 days ago. I went to the doctors in the country I am currently working in. (which also jails you and takes ur visa if you contract hiv or hep) They told me not to worry... Read more »