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Missed Dose Fosamprenavir

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An Overview of Lexiva (Fosamprenavir, Telzir)

FOS-am-pren-a-veer Brand Name: Lexiva Other Name(s): Fosamprenavir calcium, GW 433908, GW433908, Telzir, VX 175, f-APV Drug Class: Protease Inhibitors Fosamprenavir, also known as Lexiva, is a type of medicine called a protease inhibitor (PI). PIs work by blocking protease, a protein that HIV needs to make more copies of itself. HIV/AIDS-Related Uses Fosamprenavir in tablet form was approved by the FDA on October 20, 2003, for...
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fosamprenavir and tenofovir interaction

Is there any drug-drug interactions that you know of between the new PI- fosamprenavir and tenofovir?...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
Thanks for your question.We have very good data about the one-way interaction-- there's no significant change in fosamprenavir's levels when dosed with tenofovir. This is different that the situation for another new PI, atazanavir. When... Read more »

fosamprenavir+/- ritovavir

Quick question I am treatment naive but about to start drug therapy. I have the option to take fosamprenavir alone (at a higher dose) or at a reduced dose with ritonavir. I read that boosting with ritonavir from the start might prevent resistance....
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
The period of greatest risk for resistance is often the first year on therapy. In order to avoid early resistance I usually use a boosted protease inhibitor (with ritonavir) until the viral load is undetectable (< 50 copies)-then I assess whether... Read more »

fosamprenavir+/- ritovavir

Quick questionI am treatment naive but about to start drug therapy. I have the option to take fosamprenavir alone (at a higher dose) or at a reduced dose with ritonavir. I read that boosting with ritonavir from the start might prevent resistance....
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
Steve-Thanks for your question. We have accumulated a lot of experience with fosamprenavir (Lexiva, Telzir) over the last years. The medication is among the best tolerated protease inhibitors (whether dosed boosted with ritonavir, or not).... Read more »

Fosamprenavir?

Hi Dr. Young,Not too long ago, i read fosamprenavir had gone through clinical trials, successfully. It appears to have great efficacy, little side effects (especially for a PI) and the once daily protocol is favorable. Why hasn't it hit the...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
Fosamprenavir (or 908) is a new HIV protease inhibitor (the follow up to the potent, but unwieldly amprenavir (Agenerase). The maker of fosamprenavir, GlaxoSmithKline has submitted paperwork to the US FDA for review; I expect that we will hear from... Read more »
Connect With Others

missed

Posted by jab, 1 Reply
missed sustiva dose, should I take it now Read more »

Hi, guys, I've been missing you all, esp AIDSTOHV

Posted by Anonymous, 1 Reply
It is so good to be back, I and my husband have been very busy with blood work, trying to get a head doc---long, long waiting list for that with an HMO, and just dealing with life in general. Also we went to the Northern Lights ALternatives, which... Read more »

HALF DOSING MY MEDS

Posted by Anonymous, 1 Reply
Hello All !! I want to tell everyone that I started taking half of the prescribed doses of my meds about 2 years ago. My T cells remain High (570) and my V load is still undetectable..
I am on viramune,ziagen and zerit. I had an uncle who died... Read more »

dosing schedule adjustment

Posted by pozartistsd, 1 Reply
hey all you experts out there! I think i may know the answer to this but would like to get some input:

I currently take my meds (Reyataz/Truvada/Norvir) once a day. I take them at 9am (with breakfast, not that you need to know that ) I would like... Read more »

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