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Methotrexate Immune Reconstitution And Hiv

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Ask the Experts

Methotrexate and CD4 counts

I am 57 and have been diagnosed with HIV(AIDS) for 3 years. My initial CD4 183, 7%, VL 83,000. Since then my labs increased to CD4 519, 21%, VL undetectable (I have been on Atripla since 1/07). I also have rheumatoid arthritis. My Rheumatologist...
Mark Holodniy, M.D., F.A.C.P., C.I.C.

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine
...sense this is a false drop given the constant CD4%. As you are likely aware MTX would affect other blood cell counts as well. HIV and RA together is always tricky to treat, as many of the RA treatments affect the immune system by attempting to... Read more »

HIV to AIDS immune system

Hello Dr. McGovern, can you tell me what changes occur in the immune system when an HIV patient... Read more »

Methotrexate and HIV Meds

Approximately six months after my HIV diagnosis (Jan 00')I was diagnossed with Psoriatic Arthritis.... Read more »
The Well Project

Immune Reconstitution

...Antimicrobial Chemotherapy 57:167-170, 2006. Crum-Cianflone NF. Immune reconstitution inflammatory syndromes: what's new? AIDS Reader 16(4):199-206, 213, 216-217; discussion 214-217. 2006. Read more »
AIDS InfoNet

Immune Restoration Syndrome

...Is Immune Restoration Syndrome? Some people who start antiretroviral therapy (ART) get health problems even though their HIV comes under control. An infection that they previously had might return. In other cases, they develop a new disease.... Read more »
The Well Project

Understanding the Immune System

... Introduction Key Organs of the Immune System HIV and the Immune System Footnotes Introduction The immune system is made up of cells and organs that protect your body Read more »
AIDS InfoNet

Immune Restoration

...Many people taking strong antiretroviral medications now have normal CD4 cell counts. However, people with HIV are getting "non-AIDS" diseases such as cancer and heart disease. These occur at higher than normal rates based on age. Recent research... Read more »
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Immune system & HIV detection

Posted by andypb, 1 Reply
...What is compromised/ supressed immune system. Does compromised/ weak immune system take more time to produce antibody to HIV infection. Would a Person having as low Cd 4 counts 350 is considered to have compromised immune system. Do such... Read more »


Posted by Anonymous, 1 Reply
...are infected and your immune system has failed to neutralize the virus. The great hope for many who believe that HIV causes AIDS is that researchers will some day develop a vaccine. But vaccines work by causing your body to produce antibodies... Read more »

Suppressed immune system

Posted by Anonymous, 2 Replies
...Hello, I was just wondering what types of things suppress your immune system, which I know can delay your HIV test from coming up positive? Read more »


Posted by Anonymous, 2 Replies
...I have read the post "window 1991", if a auto immune disease exists, than the Elisa test could not work at 3 months, is it correct???? Read more »