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Metabolic Complications Of Antiretroviral Drugs

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AIDS InfoNet

Taking Current Antiretroviral Drugs

Nucleoside and Nucleotide Analog Reverse Transcriptase Inhibitors (Nukes) Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs) Combination Therapy Protease Inhibitors Fusion Inhibitors Integrase Inhibitors 1. Nucleoside and Nucleotide Analog Reverse Transcriptase Inhibitors (Nukes) Drug Daily Pills (Adults)* How to Take and Store Side Effects Notes Abacavir (Ziagen) 2 (300 mg: 1, 2x/day or 2, 1x/day) No...
Ask the Experts

What are the complications of getting pregnant while on Viramune?

I was diagnosed hiv + in Dec 98'. I have been on a combination of Viramune and Combivir since October of 1999, with no major complications or side affects. My viral load is undetected and my tcells go between 550 and 950. I want to get...
John L. Sullivan, M.D.

Response from John L. Sullivan, M.D.

University of Massachusetts, Medical School
The comments concerning Viramune and pregnancy are true for all antiretrovirals as they have not been proven safe in pregnant women; many HIV infected women have been treated with Viramune containing regimens and have had no complications; based on... Read more »

complicated test question

Hello Doctor Bob,Heres an interesting scenario for you. ok well i received a three and half month negative after getting an unprotected bj from girl friend. about four months after testing i started dating another girl and she started to go down on...
Robert J. Frascino, M.D.

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation
Hello,I agree your risk is "really low to nonexistent" whether the giver of your "half-a-second" blowjob was HIV positive or negative!Yes, $300 can provide care for a year, including the provision of antiretroviral drugs for a... Read more »

Epilepsy & Anti-retrovirals

Have there been any studies of the drug interaction between anti-retoviarals, i.e. Truvada & viramune, and epilieptic drugs such as epilim. I started taking truvada and viramune, eight weeks ago and recently auras have returned. Also the epilim...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
I am unaware of any published data looking at interaction between valproic acid and nevirapine. Valproic acid is metabolized through the cytochrome 450 systemm in the liver so there may be a potential interaction in occasional patients. if any... Read more »

Delavirdine interactions with Indinavir and other antiretrovirals.

Hi Dr. Cohen!Bob Frascino spoke to a group of us in Monterey, CA last week and began for the first time to explain why I have remained undetectable for so long(4+ years) on the same five drug regimen even though my dosing schedule was not precise....
Cal Cohen, M.D., M.S.

Response from Cal Cohen, M.D., M.S.

Harvard Medical School
Yup. Very clear. Hope the answer is equally lucid.Yes -- delavirdine (for simplicity I'll abbreviate it DLV) does have similar effects on the p450 system as does ritonavir. Not as potent but similar. So yes you can dose reduce the IDV to... Read more »
Connect With Others

"Positive living" eclipsed by ARV (Antiretroviral

Posted by bradford, 1 Reply
"Positive living" eclipsed by ARV (Antiretroviral) drive

Originally, it seemingly appeared that anyone infected with HIV would progress to disease and die. This has long since been realized to no longer be true. We have individuals all over the... Read more »

HIV/AIDS drugs saved my life!

Posted by bradford
HIV/AIDS drugs saved my life!

From the time I was told I had six months to live by an AIDS specialist in 1985, I learned from other people infected with HIV and included supplements and complementary therapies. These kept me healthy and were... Read more »

Anyone else taking Drug Holidays?

Posted by Anonymous, 2 Replies
Hi everyone, new to this Bulliten Board, but was wondering if anyone else has taken a drug holiday, I know most doctors DO NOT agree with doing this, but was just wondering.


Read more »

STI--Going Off Drugs

Posted by lawrencegoodman
I am a reporter working on a story about STI and the possible overprescribing of antiretrovirals/HAART. I am looking for people who might have been put on the drugs in the mid-90s and have gotten off them to do STI. I am looking to find out about a... Read more »

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