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Spotlight Series: HIV Stigma and Discrimination

Long Term Side Effects Of Ziagen

Here's a taste of what has to offer on this topic:
Get the Facts
The Well Project

Side Effects of HIV Drugs

... Table of Contents Side Effects and HIV Drugs Being Informed About Side Effects Helps Women and Side Effects Taking Care of Yourself Side Effects and HIV Drugs Over the years, drugs have been developed that can treat a wide range of medical
Ask the Experts

Why should I avoid long term exposure to AZT?

Dr. Pierone, You recently answered a question form someone about switching from Trizivir to combivir. In your answer, you suggested avoiding combivir to reduce long term exposure to AZT, one of the two drugs in combivir, in favor of Epzicom or...
Gerald Pierone, M.D.

Response from Gerald Pierone, M.D.

AIDS Research and Treatment Center of the Treasure Coast
...Hello and thanks for posting. The main reason for choosing Ziagen or Viread ahead of AZT is because these nucleosides are generally better tolerated and more potent. In addition, Viread has been shown to be more effective than AZT in a head Read more »

Long term "salvage" therapy side effects

I am a person who has been hiv+ since the 80's and was one of the first people to get the hiv antiblody test after its release. I started meds soon after there was something available besides AZT, due to a random CD4 count of 30. I then began...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
...there is no good answer other than--watch closely since patients like yourself are the real laboratory for what happens over the long term. As I tell patients - no lab rat has taken those meds for as long as some of our patients so they have to... Read more »

trizivir, ziagen = death

My question concerns why Ziagen (Trizivir) is even on the HIV market since, if someone forgets to take it for a day and then goes back to it because let us say he is not well-informed, it could lead to death. Why would a drug like this be on the...
Brian Conway, M.D.

Response from Brian Conway, M.D.

University of British Columbia
...It is correct to say that Ziagen (either given alone or as a component of Trizivir)may have significant side effects. In 3% cases, there can be a hypersensitivity reaction, with fever, rash and other systemic problems. If the Ziagen Read more »

Side Effects LT Survivor

Hi: I am a long term survivor -- nearly 20 years -- generally experiencing good health. I have been taking meds since my diagnosis. I am currently on the combo: sustiva, ziagen, and videx. I have been taking this combo for many months and early on...
Brian Conway, M.D.

Response from Brian Conway, M.D.

University of British Columbia
...Congratulations on being a long-term survivor. At this stage, the type of symptom that you describe is quite general, and could be due to a number of cardiac or neurologic Read more »
Test Positive Aware Network


...forms the nucleoside backbone for nearly all HAART regimens since the HAART era began. While its use is often associated with long term successful virus suppression, it is one of the drugs in the regimen to which resistance is commonly observed... Read more »
Project Inform

Report from the HAARTland perhaps to one small study of a single drug. An initial dose-ranging study of the new fusion inhibitor, T-20 (pentafuside), gave the drug to one of the most difficult patient populations ever treated in a clinical trial setting.... Read more »
Canadian AIDS Treatment Information Exchange

Choosing Treatment: With What

...most people have their best response to their first regimen, it is obviously important to choose one that has proven potency, side effects you can tolerate, and a dosing schedule that you can really, truly adhere to. This will give you the best... Read more »

An Overview of Ziagen (Abacavir)

... Brand Name: Ziagen Other Name(s): FABC, ABC sulfate, Abacavir sulfate, Sulfato de abacavir Drug Class: Nucleoside Reverse Transcriptase Inhibitors Abacavir sulfate, also known as Ziagen or ABC, is a type of medicine called a... Read more »
Connect With Others

26 years AIDS survior

Posted by AaronK, 3 Replies
...I had AIDS for many years now and was the lucky one's to surive... the clinical studies.... long term side effects... and the worst isolation. I'm 26 years old and i was dianosed in 1988 when i was five years old. My parents didn't Read more »

Thanks for your support and any more advice?

Posted by motherinlaw, 3 Replies
...where this will lead, but she is going to go stay with her mother who will "nag" her to take her meds. This does not seem lke a long term solution unless she intends to stay with her mother. The doctors strongly advised her to stay in the... Read more »

Toxicity: Your Experiences

Posted by Anonymous
...available in a new study on a once daily dosing schedule. My question is, what do u think about drug side effects/toxicity over the long term? Does anyone do a combo like this? Read more »


Posted by Anonymous, 1 Reply
...prescribed at the time. I believe this is what killed him, not HIV. I am astounded and continue on my half doses hoping that the long term side effects, which are unknown,will be lightened. I know there is some research now about half-dosing. I... Read more »