Long Term Side Effects Of Zerit

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Stavudine (Zerit)

What Is Stavudine? Stavudine (Zerit) is a drug used as part of antiretroviral therapy (ART). It is manufactured by Bristol-Myers Squibb. The original patent on stavudine has expired. The U.S. Food and Drug Administration (FDA) approved generic forms of stavudine for sale in the U.S. and under PEPFAR (see Fact Sheet 475 ). Stavudine is also known as d4T or didehydro-deoxythymidine. Stavudine is the most commonly used anti-HIV medication...

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Long term side effects of Hiv Meds

What are the long term side effects of the so called triple cocktails.I have been taking Kaletra,Zerit and Epivir for about 2 years and am concerned about the long term side effects. I am worried that the drugs will kill be before Aids does....

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine

The mortality from AIDS is high when the CD4 count is < 200. In the days before potent therapy, I had a patient dying weekly (average age = 30s) and they suffered through an average of 4 and a half AIDS defining events before it all became too... Read more »

Long term "salvage" therapy side effects

I am a person who has been hiv+ since the 80's and was one of the first people to get the hiv antiblody test after its release. I started meds soon after there was something available besides AZT, due to a random CD4 count of 30. I then began...

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine

Great question for which there is no good answer other than--watch closely since patients like yourself are the real laboratory for what happens over the long term. As I tell patients - no lab rat has taken those meds for as long as some of our... Read more »

Avoiding Long term Side Effects

Thank you for the great work you do on this forum.I am from South Africa but I am fortunate enough to have access to ARV therapy.I was diagnosed in April 2004 during seroconversion whilst my antibody test was still negative. At the time my viral...

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine

Great questions and I am delighted to hear that you are on therapy---if only that were true everywhere! The regimen you are on has a great reputation for effectiveness. I have been decreasing my use of D4T out of concern for an relatively... Read more »

Viracept/Epivir/Zerit vs. Sustiva/Epivir/Zerit

I have been positive for 3 years and doing well. Undetectable viral load, t-cells around 600. I started meds with Epivir/Zerit/Viracept and recently dropped the Viracept for Sustiva. I was told that the Viracept was the cause of the fat pad that...

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine

Switching to Sustiva "saves" the protease class for later use and can be a part of a long-term treatment plan. Your current regimen still can cause fat problems (all 3 meds) and generally the fat pads haven't gotten better on your... Read more »

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long term side effects(lack of)

Posted by Anonymous

For women who have been on antivirals continuously for a while (more than four to five years)and have not had any side effects or minimal ones,could you please share your experiences. What you are taking, what you experienced(if it resolved while on... Read more »

long term side effects

Posted by Anonymous, 1 Reply

It would be interesting to hear from anyone that has been on antivirals for a long time(more than 4 years continously)that have minimal or NO side effects. Physical(appearence wise as well as internal) IF anyone out there falls into this catagory... Read more »

psychological effects with long-term survivor

Posted by Anonymous, 4 Replies

I guess I am needing to know if there are any people out there who have really been in some sort of denial for years until first symptoms hit. I feel like a fool, but I've been positive since 84 and really have been in denial until getting so so... Read more »

Report Side effects of Zerit and Videx

Posted by Anonymous, 2 Replies

If you have experienced side effects, especially peripheral neuropathy, from Bristol Myers Squibb's drugs Zerit and Videx please report them to the Food and Drug Administration (FDA). This is done by calling the FDA's Medwatch toll free phone number Read more »

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