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Long Term Side Effects Of Kivexa

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AIDS InfoNet

Epzicom/Kivexa (Abacavir + Lamivudine)

What Is Epzicom? Epzicom is a pill that contains two drugs used to fight HIV: abacavir (Ziagen) and Epivir (lamivudine, 3TC). Epzicom is manufactured by ViiV Healthcare. Outside the US, it is called Kivexa. Generic versions have been tentatively approved under PEPFAR (see Fact Sheet 475 ). The drugs in Epzicom are called nucleoside analog reverse transcriptase inhibitors, or nukes. These drugs block the reverse transcriptase enzyme. This enzyme...
Ask the Experts

Combivir change to Kivexa (Epzicom)

Hi. I took Combivir together with Sustiva for 3 1/2 years, virus load undetectable almost immediatly CD4 always around 250, but the last year around 700. I do a lot of sports (triathlon), and noticed that during a big effort (biking), my muscles...
Gerald Pierone, M.D.

Response from Gerald Pierone, M.D.

AIDS Research and Treatment Center of the Treasure Coast
Hello and thanks for posting. There is evidence that AZT has more long-term mitochondrial toxicity than the abacavir (Ziagen) which is in Kivexa (Epzicom). Since mitochondria are the energy producing units of the cell, it makes sense to switch in a... Read more »

? change from Combivir to Kivexa?

I have been taking AZT + 3TC (either separately or since 1999 as Combivir) since seroconversion in 1996, first with PIs, and since 2001 with Efavirenz. I get great results - VL is consistenly undetectable, and T clees range 700-900. Lipodystrophy...
Gerald Pierone, M.D.

Response from Gerald Pierone, M.D.

AIDS Research and Treatment Center of the Treasure Coast
My friend the writer has a circa 1980 IBM electric typewriter which he still uses. He has this stuff called 'white out' that he uses to cover up his mistakes and type over them. Why hasn't he moved on to computers and word... Read more »

Long term side effects of Epzicom

Please help me with any knowledge you have so far on the long term side effects of Epzicom. I was on Combivir and Viramune from the beginning of year 2003 to 2006. I tolerated the drugs well, except for that I had constantly a light anemia, which...
Joseph McGowan, M.D., F.A.C.P.

Response from Joseph McGowan, M.D., F.A.C.P.

North Shore University Hospital
The symptoms of depression and the pain in your legs that you are describing is not something I have observed with Epzicom in my clinical practice and is not something that has been mentioned as a consistent issue in people who have taken Epzicom.... Read more »

Long Term Side Effects

Has there been any findings on the long term side effects from HIV & other combined meds now that HIV+ people are living longer? ...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
There is an increasingly growing experience with long-term use of effective antiretroviral therapy which has been available now for 10+ years. Many newer regimens appear to have lower rates of side effects but interpretation is hampered by less... Read more »
Connect With Others

long term side effects(lack of)

Posted by Anonymous
For women who have been on antivirals continuously for a while (more than four to five years)and have not had any side effects or minimal ones,could you please share your experiences. What you are taking, what you experienced(if it resolved while on... Read more »

long term side effects

Posted by Anonymous, 1 Reply
It would be interesting to hear from anyone that has been on antivirals for a long time(more than 4 years continously)that have minimal or NO side effects. Physical(appearence wise as well as internal) IF anyone out there falls into this catagory... Read more »

PeP (Truvada and Kaletra) 28 day cycle... Long Term effects?

Posted by Screen1001
Hello all, I just started taking Truvada and Kaletra 3 days ago to provent being infected. After I am done with my 28 day cycle is it common for the side effects to remain long term? Right now I have had a very upset stomach and nausia for 3 days.... Read more »

psychological effects with long-term survivor

Posted by Anonymous, 4 Replies
I guess I am needing to know if there are any people out there who have really been in some sort of denial for years until first symptoms hit. I feel like a fool, but I've been positive since 84 and really have been in denial until getting so so... Read more »