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Long Term Side Effects Of Darunavir

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Darunavir (Prezista)

What Is Darunavir? Darunavir is a drug used as part of antiretroviral therapy (ART). It is also called Prezista TM and used to be called TMC114. It is manufactured by Tibotec Pharmaceuticals. Darunavir is a protease inhibitor. These drugs prevent the protease enzyme from working. HIV protease acts like a chemical scissors. It cuts the raw material for HIV into specific pieces needed to build a new virus. Protease inhibitors "gum up" these...
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Darunavir or not to Darunavir + Low WBC

Hi Joe,I have another question for you. I have recently seen my consultant, and he has suggested changing PI's from Atazanavir to Darunavir. He quotes a few studies that suggest additional benefit for DRV. At the moment I'm undetectable on...
Joseph McGowan, M.D., F.A.C.P.

Response from Joseph McGowan, M.D., F.A.C.P.

North Shore University Hospital
Michael,Thanks for your questions. Darunavir is now approved for both first line treatment as well as for treatment experienced patients. It is a very potent protease inhibitor, but potency does not seem to be an issue with your regimen since you... Read more »

Prezista/Darunavir

What is the side effects of Prezista/Darunavir?Any lipoatrophy or lipodystrophy?...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
Good question. The best studies to evaluate lipodysrophy issues is when used in treatment naive patients comparing one regimen to one of the standard of care regimens. Increasingly, the back bone nuke regiments are abacavir or tenfovir + either 3TC... Read more »

Long term side effects of Epzicom

Please help me with any knowledge you have so far on the long term side effects of Epzicom. I was on Combivir and Viramune from the beginning of year 2003 to 2006. I tolerated the drugs well, except for that I had constantly a light anemia, which...
Joseph McGowan, M.D., F.A.C.P.

Response from Joseph McGowan, M.D., F.A.C.P.

North Shore University Hospital
The symptoms of depression and the pain in your legs that you are describing is not something I have observed with Epzicom in my clinical practice and is not something that has been mentioned as a consistent issue in people who have taken Epzicom.... Read more »

Long Term Side Effects

Has there been any findings on the long term side effects from HIV & other combined meds now that HIV+ people are living longer? ...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
There is an increasingly growing experience with long-term use of effective antiretroviral therapy which has been available now for 10+ years. Many newer regimens appear to have lower rates of side effects but interpretation is hampered by less... Read more »
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long term side effects(lack of)

Posted by Anonymous
For women who have been on antivirals continuously for a while (more than four to five years)and have not had any side effects or minimal ones,could you please share your experiences. What you are taking, what you experienced(if it resolved while on... Read more »

long term side effects

Posted by Anonymous, 1 Reply
It would be interesting to hear from anyone that has been on antivirals for a long time(more than 4 years continously)that have minimal or NO side effects. Physical(appearence wise as well as internal) IF anyone out there falls into this catagory... Read more »

PeP (Truvada and Kaletra) 28 day cycle... Long Term effects?

Posted by Screen1001
Hello all, I just started taking Truvada and Kaletra 3 days ago to provent being infected. After I am done with my 28 day cycle is it common for the side effects to remain long term? Right now I have had a very upset stomach and nausia for 3 days.... Read more »

psychological effects with long-term survivor

Posted by Anonymous, 4 Replies
I guess I am needing to know if there are any people out there who have really been in some sort of denial for years until first symptoms hit. I feel like a fool, but I've been positive since 84 and really have been in denial until getting so so... Read more »