Long Term Side Effects Of 3TC

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An Overview of Combivir (AZT/3TC)

la-MI-vyoo-deen, zye-DOE-vyoo-deen --> Brand Name: Combivir Other Name(s): ZDV/3TC Drug Class: Nucleoside Reverse Transcriptase Inhibitors Lamivudine/zidovudine is a fixed-dose combination tablet of two antiretroviral medicines, called nucleoside reverse transcriptase inhibitors (NRTIs). Lamivudine/zidovudine works by disrupting one of the early steps in the HIV life cycle, called reverse transcription. During normal...

Ask the Experts

Old resistance to 3tc and use of combivir

Dear Dr ShererI am long term diagnosed and have been on HAART since the mid 1990's. During that time i have only developed resistance whilst on a two drug (3tc/d4t) combination in about 1996.I have had long term problems with drug side effects...

Response from Renslow Sherer, M.D.

University of Chicago Hospitals

HIV physicians often prescribe 3TC to patients known to have resistance to it for several reasons - it still retains a one-half log viral log decline, even with the resistance, and it also impairs viral 'fitness'.If the only reason to... Read more »

T20 with 3TC?

I notice that T20 and 3TC have the fewest and least health threatening side effects. Also, neither causes grotesque visual effects, like myopathy or lipoatrophy. Can the two be taken in combination? Or are they not potent enough together?...

Response from David Wohl, M.D.

University of North Carolina - Chapel Hill

T-20 is very new so the long term effects of this agent, if any, are not known. 3TC actually suffers from the opposite - it has been around a long time but is always taken with other drugs that tend to overshadow it in the efficacy and toxicity... Read more »

Viread/3TC/Sustiva

Hello,Thank you for the excellent work you do on this site. Your help is really appreciated.For those starting their first HAART regimen and wishing to start on a PI-sparing combination, it seems that Combivir/Sustiva has always been an excellent...

Response from Gerald Pierone, M.D.

AIDS Research and Treatment Center of the Treasure Coast

Hello and thanks for posting. I do favor the use of once daily regimens like Viread, Epivir, and Sustiva for initial management of HIV infection. There is nothing wrong with Combivir and Sustiva and we have many patients doing well on it for years.... Read more »

Viread/3TC/Sustiva

Hello, Thank you for the excellent work you do on this site. Your help is really appreciated. For those starting their first HAART regimen and wishing to start on a PI-sparing combination, it seems that Combivir/Sustiva has always been an excellent...

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES

Thanks for your question and kind comments.You've mentioned a couple of the most frequently prescribed first-line treatments. The later regimen (tenofovir/3TC/efavirenz) is indeed a well tolerated and well studied combination. There is no... Read more »

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Reyataz,Norvir, Kivexa [abacavir/3TC, Epzicom].

Posted by Mondo

Is there anyone here at the forum taking the following cocktail?
I'm taking Reyataz[atazanavir], Norvir [ritonavir] and Kivexa [abacavir/3TC, Epzicom]. I would be interested to know how you are going with it and any problems or side effects that you... Read more »

long term side effects

Posted by Anonymous, 1 Reply

It would be interesting to hear from anyone that has been on antivirals for a long time(more than 4 years continously)that have minimal or NO side effects. Physical(appearence wise as well as internal) IF anyone out there falls into this catagory... Read more »

long term side effects(lack of)

Posted by Anonymous

For women who have been on antivirals continuously for a while (more than four to five years)and have not had any side effects or minimal ones,could you please share your experiences. What you are taking, what you experienced(if it resolved while on... Read more »

psychological effects with long-term survivor

Posted by Anonymous, 4 Replies

I guess I am needing to know if there are any people out there who have really been in some sort of denial for years until first symptoms hit. I feel like a fool, but I've been positive since 84 and really have been in denial until getting so so... Read more »

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