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Lipodystrophy Insulin Resistance

Here's a taste of what has to offer on this topic:
U.S. Centers for Disease Control and Prevention

Insulin Resistance in HIV Lipodystrophy Syndrome

Researchers recently completed a study identifying the incidence of insulin resistance in HIV-patients who exhibit signs of lipodystrophy. The authors noted two significant metabolic changes occurring in those patients, including significant... Read more »
Canadian AIDS Treatment Information Exchange

Insulin Resistance and Diabetes

Protease inhibitors have been tied to an increased incidence of glucose intolerance and decreased sensitivity to insulin, the hormone that is needed for the uptake of glucose (sugar) into the body's cells. When that process isn't working properly,... Read more »

The Role of Nucleoside Analogs in the Development of Insulin Resistance

Given that HIV-infected patients can now survive for decades on antiretroviral therapy, comorbidities such as lipodystrophy and insulin resistance have moved to the forefront of HIV management. Yet, much remains to be discovered about these... Read more »
Ask the Experts

lipo & insulin resistance

Is lipodystrophy caused by insulin resistance? The cells not receptive to the insulin and not allowing the glucose into the cells?...
Cade Fields-Gardner M.S., R.D.

Response from Cade Fields-Gardner M.S., R.D.

The Cutting Edge
Insulin resistance has been considered a culprit in fat redistribution. Chronic HIV infection, medications, response to treatment from very low CD4 counts or very high viral loads, hormonal and organ function alterations, co-existing diseases,... Read more »

Leptin use for Insulin Resistance?

I have a question about the possible use of leptin for insuline resistance. I found the following article on dealing with Insulin resistance and HIV. The article mentions... "Leptin...
Graeme Moyle, M.D.

Response from Graeme Moyle, M.D.

Chelsea and Westminster Hospital
Leptin, the 'satiety' factor produced by fat cells is not available as a medication. It has been studies in a small number of people with inherited forms of lipodystrophy and found to help a range of metabolic disturbances. However, it has... Read more »

Follow up to your advice to have a glucose tolearnce or insulin resistance test

Hello, Dr. Moyle,I wonder if you can clarify something for me: I asked my doctor for an insulin resistance test and glucose tolerance test recommended by you to help determine the cause of my new found truncal obesity and addition of 7 inches to my...
Graeme Moyle, M.D.

Response from Graeme Moyle, M.D.

Chelsea and Westminster Hospital
Several studies (your Doctor may be familiar with one by Carr et al, another by Hadigan et al, there are also AACTG recommendations by Dube et al) have shown that for people with HIV a random or fasting glucose only pick ups up a minority of people... Read more »

Lipodystrophy (LIPODYSTROPHY)

I'm trying to find CURRENT information about lipo treatment options, but everything I find, including on this site, is over 2 years old. Can you point me to anything newer. I've been advanced/full-blown (technically) for 15 years, and...
Robert J. Frascino, M.D.

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation
Hi,The best source for current information about lipodystrophy (lipoatrophy and lipohypertrophy) should be your HIV specialist physician. Treatment options depend on your specific case. There is current information on treatment options on this site... Read more »
Connect With Others

lipodystrophy from protease inhibitors

Posted by Anonymous, 4 Replies
I have known about my HIV+ status now for 6 years, and God has blessed me with continued good health. I have accessed all the major medications, plus vitamins to help fight the disease. Once I started taking the new protease inhibitors, I started... Read more »


Posted by Anonymous, 1 Reply
anyone who will talk about this?

Read more »

Resisting Resistance - A Story

Posted by Survivor, 1 Reply
Personal Perspective: Resisting Resistance

By Matt Sharp

Spring 2006

In a little over four months I will turn fifty. When I was diagnosed with HIV in 1988 I never dreamed I'd reach forty. I've survived a long battle with HIV, and it has not been... Read more »

exercise and PI lipodystrophy

Posted by Anonymous, 3 Replies
i have been on zerit, epivir and crix for more than one year.
i have lipodystrophy (no more buttocks, fat loss in face and a paunch). I have always been an avid exerciser -- my doc has told me to STOP exercising, that it worsens the situation.
i... Read more »