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Laboratory Control Values For Cd4 And Cd8 T Lymphocytes

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CD4 (T-Cell) Tests

What Are CD4 Cells? CD4 cells are a type of lymphocyte (white blood cell). They are an important part of the immune system. CD4 cells are sometimes called T-cells. There are two main types of CD4 cells. T-4 cells , also called CD4+, are "helper" cells. They lead the attack against infections. T-8 cells (CD8+) are "suppressor" cells that end the immune response. CD8 cells can also be "killer" cells that kill cancer cells and cells infected...
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CD4 and CD4/CD8 ratio

Dear Cal, I have been recently diagnosed HIV+ (June 02) and have some questions regarding both the CD4/CD8 ratio and CD4 which do not seem to be spoken about as much as the CD4 absolute.My first question is what exactly are CD8 cells? What happens...
Cal Cohen, M.D., M.S.

Response from Cal Cohen, M.D., M.S.

Harvard Medical School
Thanks Jim - glad this helps.So - about these cell counts. We simplify the immune system to make it easier to count and report things. And one important simplification is this one - we can distinguish two major types of important cells in the... Read more »

history of cd4 and cd8 lymphopenia but hiv 1 and hiv 2 and western blot has been ruled out

my cd4 count is at 478/ul lymph is at 36.8% my cd8 count is at 113/ul lymph 8.7% but have never tested pos for hiv 1 or hiv 2 or western blot . in 2005 i had a pneumocystis carinii pneumonia i was also tested and tested neg for hiv . i was ok after...
Robert J. Frascino, M.D.

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation
Hello,You should be evaluated and treated by a clinical immunologist. There are other immunological conditions that can cause lymphopenia other than HIV-1 or HIV-2. It appears that HIV has more than been ruled out by your 32 negative tests!... Read more »

CD4 percentage & CD4/CD8 ratio

There seems a lot of information about the average annual decline in CD4 cells (50-75 or 3% per year)and thus one might be able to estimate how long it will take for one's own absolute CD4 count to fall below 500 (or the critical 350 mark), BUT...
Mark Holodniy, M.D., F.A.C.P., C.I.C.

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine
I don't have an answer for those numbers.... Read more »

CD4 count up but CD4/CD8% all over the place

Hi. Since I got diagnosed my CD4 count has been steadily increasing from 213 - 325 over 6 months (not on meds yet). However the CD4-CD8% has been all over the place: 19%-24%-21% & last test 11%. I haven't been sick in any way I'm aware...
Mark Holodniy, M.D., F.A.C.P., C.I.C.

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine
That is a significant variation in CD4% that one normally does not see, unless there are other ongoing medical conditions, medications, or different assays for CD4 counts involved. I am not so concerned about the variation between 19-24%, but I am... Read more »
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cd4 cd8

Posted by Anonymous, 3 Replies
please can somebody tell me if your cd count percentage
was 57 what would it be in absolute count. nobody knows at my doctors offfice and the lab won't tell me Read more »

Good News... PCR/CD4/CD8 results!!

Posted by uglyduck, 4 Replies
At, 18 days post exposure:

PCR = Undetectable (or as one of my HIV specialist said, NEGATIVE).
CD4: 476 (kind of low, but my HIV specialist says that is normal)
CD8: 494 (OK)
CD4/CD8 %: 27% (He says is OK).

Well, I just got my resutls and saw one of... Read more »

Use of cd4/cd8

Posted by Anonymous
Hi,
dropping by this bulletin-board, I see there is a lot of use and abuse of t-cell subsets among worried wells. To put things in perspective - cd4/cd8-ratios were used as a surrogate marker of HIV-infection among blood donors at a US hospital... Read more »

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