Kaletra Dosing Change With Viramune

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Kaletra

Brand name: Kaletra Generic name: lopinavir/ritonavir, or LPV/r Class: Protease inhibitor (PI) Manufacturer: Abbott Laboratories, www.kaletra.com , (800) 222-6885 AWP: $904.99/month for tablets, $420.95 for 160 mL solution Standard Dose: Two tablets (200 mg lopinavir/50 mg ritonavir) twice a day or four 200/50 mg tablets once daily for people with less than three lopinavir resistance-related mutations, as shown on a resistance...

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Adjust Abacavir dose with Kaletra?

Is it true that Kaletra will lower blood levels of abacavir? If so, should an adjustment be made to the abacavir dosage? Thanks....

Response from Cal Cohen, M.D., M.S.

Harvard Medical School

There is no dose change of abacavir with Kaletra that I am aware of.In general, Kaletra, a combo PI that contains a small amount of ritonavir, will inhibit the activity of an enzyme that metabolizes many of the other PIs. This means that if... Read more »

Switching from Kaletra to Viramune follow-up question

Dr. Boyle: Thank you for your answer. Here is a follow-on question: Can I switch to Sustiva now or in a few weeks (I started it in place of Kaletra on 1-7-04)? Can I switch back to Kaletra now or in the future? I will get my lipids down and my...

Response from Brian Boyle, M.D., J.D.

Cornell University, Weill Medical College

First, if you're having "itching and some rash" on the 200mg dose of nevirapine you should not increase the dose until you have been evaluated by your doctor as that places you at higher risk for severe rash once you go to the 400mg... Read more »

Truvada+Kaletra or Truvada+Viramune

Hi, I'm ready to start meds for first time and my Dr. has recommended two options for me. Truvada+Kaletra or Truvada+Viramune. I would like the option that has the least side effects and least toxic. I'm a little concerned with the...

Response from Edwin DeJesus, M.D., F.A.C.P.

Both of those regimens are very effective in treating HIV, but the side effects profiles are quite different. Kaletra has been associated more with gastrointestinal side effects, such a change in bowel movements, and alterations on your lipids,... Read more »

High Dose Kaletra

I have 2 questions for you:1. If a person is resistant to Kaletra, Can that person over come the resistance by increasing the dose to 4 a day (that is what my Dr. wants me to do)?2. Also have you heard about using oral Valtrex for CMV...

Response from Judith A. Aberg, M.D.

Washington University, St. Louis School of Medicine

1. The reason for increasing the Kaletra dose to 4 tablets twice a day is because you may be taking a medication that interacts with Kaletra (can cause the Kaletra levels to be too low). It is recommended that you take 4 Kaletra tablets when you... Read more »

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New Kaletra Formulation.....

Posted by Anonymous, 3 Replies

Hello.
I am looking at changing from Sustiva to Kaletra (My Nuke backbone is Truvada), however I have concerns about the side effect profile of Kaletra.
I hear that the newer formulation of Kaletra has less side effects that the old one - has anyone... Read more »

Kaletra body changes..

Posted by Lovinlife, 1 Reply

I recently started taking Kaletra. Has anybody experienced body changes on Kaletra? My doctor didn't mention anything about it but after looking on line, I see a lot of people saying that Kaletra causes lipodystrophy.

Anybody have experience with... Read more »

First Regimen = Sustiva + Combivir + Kaletra?

Posted by placation, 4 Replies

Hey guys (and gals). I am sure this has been addressed in some other post through some other thread in the past, but it would take forever to try to find those messages. So, here's my question and my issues...

My doc subscribed Sustiva + Combivir +... Read more »

Abacavir,viramune,viread

Posted by Anonymous, 2 Replies

I'm on day 4 of my new combo Abacavir,viramune,viread, epivir and it totally sucks. I feel lousy all of the time. Is this typical when starting this combo? This is my 4th combo since diagnosis...

Read more »

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