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Is Trizivir Still An Effective Drug

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Get the Facts
AIDS InfoNet

Trizivir (Zidovudine + Lamivudine + Abacavir)

What Is Trizivir? Trizivir is a pill that contains three antiretroviral drugs (ARVs) used to fight HIV: zidovudine (Retrovir, AZT), lamivudine (Epivir, 3TC) and abacavir (Ziagen). Trizivir is manufactured by ViiV Healthcare. Generic versions have been tentatively approved under PEPFAR (see Fact Sheet 925 ). The drugs in Trizivir are called nucleoside analog reverse transcriptase inhibitors, or nukes. These drugs block the reverse transcriptase...
Ask the Experts

trizivir or trizivir plus viramune

Last month, blood tests show a blip 50 instead of less than 40 on trizivir alone after being undetectable for 2 years. My doctor recommended adding viramune to preclude possible resistance with trizir alone. Please advise!...
Renslow Sherer, M.D.

Response from Renslow Sherer, M.D.

University of Chicago Hospitals
The use of trizivir alone has recently been shown to be less successful at controlling viral replication than three drug regimens containing efavirenz after 48 weeks. For this reason, many physicians are following patients on trizivir alone more... Read more »

Trizivir and Drug Resistance

Dr. Young,If one has a low viral load, is Trizivir a good regimen for treatment naive patients. I've read a lot about resistance with Trizivir (because all the drugs are in one class?)..but I am looking for something simple and tolerable..but...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
Thanks for your question.Trizivir is a very attractive treatment regimen because of it's simplicity and side effect profile. Resistance is a concern about any drug regimen, though I'd have to say that well monitored, Trizivir's... Read more »

Taking a second drug holiday with just Trizivir

I am taking this 2nd drug holiday after being undetectable for 10 years with diffferent meds with an averageof 800 T-cells. My first drug holiday in 2000 was due severestomach pain after taking Viracept and Combivir. It took three years for my...
Joseph McGowan, M.D., F.A.C.P.

Response from Joseph McGowan, M.D., F.A.C.P.

North Shore University Hospital
I would not recommend a drug holiday if you need to use INH prophylaxis. If your virus is suppressed with Trizivir, I would stick with it. You should have your liver monitored by blood tests while you are on the INH. Also, do not drink alcohol... Read more »

Should I change drugs to new combo TRIZIVIR

I currently am on a triple drug therapy of Abacavir, Videx and Sustiva. My doctor took me off of a Fortovase, Norvir, Zerit and Videx, not because I had resistance but because I had issues with lypodistrophy, high cholesterol and triglycerides. I...
Mark Holodniy, M.D., F.A.C.P., C.I.C.

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine
Trizivir contains AZT, 3TC, and Abacavir. So you would be getting two new and one old drug. AZT can have it's own side effects primarily flu-like symptoms, and anemia. Videx or ddI was given to thousands of people alone or in combination with... Read more »
Connect With Others

Trizivir??????

Posted by Anonymous
I am currently taking epivir, zerit and viracept, but am thinking of switching to Trizivir (epivir,retrovir and ziagen in one tablet). Does anyone have any experience with Trizivir? What kind of side effects? Does it contribute to lypodistrophy less... Read more »

trizivir

Posted by Anonymous, 4 Replies
Does anyone else who takes Trizivir have really severe stomach pain?
Also, I am batteling with Lymphoma. Read more »

Isentress Drug - Side Effects?? HELP

Posted by design36, 1 Reply
I have been taking Isentress for about a month...Adnormal dreams, Insomnia, Excessive fatique have been side effects and seem to be ones for a lot of people. Does anyone have experience with this drug? Did the side effects get better? How long... Read more »

Thai-Chinese Anti-HIV drug 89% effective oppinions

Posted by Anonymous
I've just read this news and I woud like to hear your opinions about it here is the link:

http://news.xinhuanet.com/english/2004-12/13/content_2328760.htm Read more »