Is Sustiva Plus Truvada A Good Combination

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Sustiva + Truvada combination

Posted by richwales, 6 Replies

Im a 26 y/o male living in UK whos been on sustiva and truvada for 4 months now my Cd4 and viral load are doing great (gone from 14% 245 to 19% 472, and 18,200 to undectable) just finding the side affects of sustiva really can be hard to cope with,... Read more »

New combined Truvada/Sustiva combination

Posted by Anonymous, 3 Replies

Hi.
Just wondered if anybody knew as to when the above co-formulated combo will be available? I s it this year?
I am starting with Truvada + Sustiva, but as I not keen on taking tablets anyway, I would rather take just 1 tablet instead of 2.
Thank you Read more »

Sustiva and Truvada

Posted by Anonymous, 8 Replies

When I first started using Sustiva and Truvada the pills seem to be beating the virus. My doctor is concerned that my numbers (VL#'s) keep going up and down. One 3 month period they will be as low as 245 the next 945 the next 485 and then 644. My... Read more »

Are you a long term Sustiva/Truvada user

Posted by soimnotalone, 2 Replies

I am curious about the long term effects of these medicines from actual users. I read the pamphlets and what doctors "claim" but I wanted some feedback from actual users
Thanks for responding ;) Read more »

About to start meds need advice please..Sustiva/Tr

Posted by HudsonJet, 3 Replies

I'm newly diagnosed positve (last week) and scared to death to say the least. My t-cell count was 248 (awaiting viral load results) My Doc suggested that he might start me on Sustiva and Truvada and I was wondering what anyone knew of these drugs... Read more »

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Switching from Sustiva + Truvada to Viramune + Truvada

Hello and thank you so much for contributing your time, knowledge and experience to so many people.I have been taking Sustiva and Truvada for about a year now and have always had difficulty staying asleep with this regimen. In addition, I feel like...

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine

The barrier to resistance for Viramune is fairly similar to that for Sustiva so I would not worry alot about the particular aspect of the switch. Viramune has less central nervous system (including sleep) disturbance related side effects than... Read more »

Results with Truvada/Sustiva combination

I recently was diagnosed and believe I have been positive for about a year to a year and a half. During my March tests, my viral load had jumped from around 100,000 in December to greater than 500,000. For this same test period my CD4 stayed around...

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES

Brian-Thanks for your post.I'd say that you've had an excellent and not unusual response to tenofovir/FTC (Truvada) and efavirenz (Sustiva, Stocrin)-- your drop in viral load is excellent as is your increase in CD4.There's some... Read more »

Truvada/Sustiva Side effects

I started the Truvada & Sustiva combination a month ago now and have been doing fairly well so far. The question I have is within the last couple of weeks I have noticed myself, for lack of a better phrase, having a lot more gas and bowel...

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES

Thanks for your post. Truvada/ efavirenz (Sustiva, Stocrin) is usually a very well tolerated medication. For most patients, the majority of symptoms are related to the psychological impact of efavirenz, while a smaller group can have side effects... Read more »

Bioequivalence Study of Sustiva and Truvada

Hi there,Could you tell me if you know of any study sites bioequivalence trials on Sustiva and Truvada? I had heard it was a good combination and would like more information.Thank you....

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine

I am not sure if you are referring to the studies of the combined Sustiva/Truvada pill that is under development. Recent bioequivalence studies comparing the experimental combined pill to the two pills (and 3 drugs total since Truvada is itself a... Read more »

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Articles

Gilead's Combination of Antiretrovirals Truvada, Sustiva Not Bioequivalent to Two Drugs Alone, Study Says

Gilead on Tuesday announced that its reformulation of a fixed-dose combination antiretroviral drug combining the company's Truvada with Bristol-Myers Squibb 's drug Sustiva is not bioequivalent to the two drugs when used separately, AFX... Read more »

Bristol-Myers Squibb Company and Gilead Sciences, Inc.

Bristol-Myers Squibb and Gilead Announce Data Supporting Bioequivalence for Single-Pill Fixed-Dose Regimen of Sustiva (Efavirenz) and Truvada (Emtricitabine and Tenofovir Disoproxil Fumarate)

New York, NY and Foster City, CA -- Bristol-Myers Squibb Company (NYSE: BMY) and Gilead Sciences, Inc. (Nasdaq: GILD) today announced they have obtained data supporting bioequivalence of a new formulation of the fixed-dose combination of... Read more »

Canadian AIDS Treatment Information Exchange

Choosing a Drug Combination

In a Capsule An effective combination of antiretroviral drugs keeps a person's viral load undetectable, is easy to take and has few side effects and long-term toxicities. Out of the large number of possible drug combinations, a few are preferred... Read more »

Appendix C: Building a Treatment Combination

In this section we will provide some background on how treatment combinations are built. We will also look at the characteristics of the different classes of antiretroviral drugs. Our goal is to provide you with enough information so that you can... Read more »

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