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Integrase Inhibitors Mode Of Action

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Ask the Experts

New Integrase inhibitor and lipodystrophy risk

There is a once a day integrase inhibitor with a non-PI booster coming up soon, isn't there? What is the integrase inhibitor called and what class does the booster belong to? Setting aside the relative newness of these drugs (and therefore the...
Gerald Pierone, M.D.

Response from Gerald Pierone, M.D.

AIDS Research and Treatment Center of the Treasure Coast
...Hello and thanks for posting. The new integrase inhibitor medication is called elvitegravir and the booster is GS 9350. The booster is one of a new class of drugs designed specifically Read more »

integrase inhibitors,where are they?

Dr. Frascino, I know we know of three crucial enzymes necessary for HIV to do its dirty work.... Read more »

ls isentress integrase inhibitors the future for hiv meds ???

Hi Dr Henry,l have been taking different hiv meds for the past 8 years, and its not much fun with... Read more »
Articles
The Body PRO

Cross-Resistance Between Integrase Inhibitors

... HIV integrase inhibitors represent a new class of antiretroviral drugs that target a crucial post-transcriptional event in the life cycle of HIV. There Read more »
Canadian AIDS Treatment Information Exchange

Integrase Inhibitor '572 Tested Against Raltegravir-Resistant HIV

... GlaxoSmithKline (GSK) has licensed an anti-HIV integrase inhibitor discovered by the Shionogi Corporation in Japan. Because of these arrangements, this drug has the complex code name S/GSK1349572 Read more »
Test Positive Aware Network

Study of New ViiV HIV Integrase Inhibitor Yields Encouraging Early Results

...Glasgow from November 7-11, it was reported by the National AIDS Treatment Advocates Project (NATAP) that the experimental integrase inhibitor S/GSK1349572 "proved a potent HIV suppressor at three doses tested in antiretroviral-naive people. ... Read more »
Test Positive Aware Network

Comparing Two Integrase Inhibitors

... It was more than a wish that integrase inhibitors became weaponry against HIV. We've waited a long time to get to this point and an even longer time to arrive at the position Read more »
Connect With Others

Integrase Inhibitor

Posted by Survivor
...(Russell, San Francisco Chronicle, 2/9). Integrase is one of the three enzymes necessary for HIV to replicate in the body, and integrase inhibitors would stop HIV from inserting its genes into normal DNA. The other two enzymes necessary for viral... Read more »

Today's LA Times Article - Integrase Inhibitors

Posted by Anonymous
Very hopeful! (Despite the sad title.) http://www.latimes.com/news/nationworld/nation/la-me-salvage2jan02,0,1565232,full.story?coll=la-home-headlines Read more »

Re: Something uplifting

Posted by SA_Intellect, 3 Replies
The link below is the response one of the doctors on The Body posted to my question. Read it. It's very positive and will hopefully add a bit of peace to some your hearts. http://www.thebody.com/Forums/AIDS/TreatExp/Archive/Pipeline/Q173719.html Read more »

Resisting Resistance - A Story

Posted by Survivor, 1 Reply
...wouldn't get much bang out of the NNRTI anyway. In addition, there are suddenly two very new drug classes on the horizon: integrase inhibitors and attachment inhibitors. This would afford me the option of adding them to TMC 114, and having two... Read more »