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Integrase Inhibitors Hiv Mechanism Action

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Ask the Experts

ls isentress integrase inhibitors the future for hiv meds ???

Hi Dr Henry,l have been taking different hiv meds for the past 8 years, and its not much fun with the side effects of the meds, l am reading about isentress integtase inhibitors and would like to know your opinion, is this the new step in hiv...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
...Raltegravir is a promising new HIV treatment known as an integrase inhibitor. It has mostly been used in patients with resistant virus in complex regimens where it has performed well. It has to be taken Read more »

integrase inhibitors,where are they?

Dr. Frascino, I know we know of three crucial enzymes necessary for HIV to do its dirty work.... Read more »

New Integrase inhibitor and lipodystrophy risk

There is a once a day integrase inhibitor with a non-PI booster coming up soon, isn't there? What... Read more »
Articles
The Body PRO

Cross-Resistance Between Integrase Inhibitors

...treatment-naive patients. A key attribute of integrase inhibitors, when used in treatment-experienced patients, is that their novel mechanism of action means that these agents are not cross-resistant with other antiretroviral classes. Two... Read more »
Canadian AIDS Treatment Information Exchange

Integrase Inhibitor '572 Tested Against Raltegravir-Resistant HIV

... GlaxoSmithKline (GSK) has licensed an anti-HIV integrase inhibitor discovered by the Shionogi Corporation in Japan. Because of these arrangements, this drug has the complex code name S/GSK1349572 Read more »
Test Positive Aware Network

Study of New ViiV HIV Integrase Inhibitor Yields Encouraging Early Results

...Glasgow from November 7-11, it was reported by the National AIDS Treatment Advocates Project (NATAP) that the experimental integrase inhibitor S/GSK1349572 "proved a potent HIV suppressor at three doses tested in antiretroviral-naive people. ... Read more »
Test Positive Aware Network

Comparing Two Integrase Inhibitors

... It was more than a wish that integrase inhibitors became weaponry against HIV. We've waited a long time to get to this point and an even longer time to arrive at the position Read more »
Connect With Others

Integrase Inhibitor

Posted by Survivor
...is hope and continued very active DRUG DISCOVERY! Merck, Gilead Release Strong Findings From Clinical Trials of Experimental Integrase Inhibitor Antiretroviral Drugs Whitehouse Station, N.J.-based Merck and Foster City, Calif.-based Gilead... Read more »

Today's LA Times Article - Integrase Inhibitors

Posted by Anonymous
Very hopeful! (Despite the sad title.) http://www.latimes.com/news/nationworld/nation/la-me-salvage2jan02,0,1565232,full.story?coll=la-home-headlines Read more »

Am I Infected

Posted by delhiguy, 3 Replies
I am 30 YO guy. Worried that I may have got infected. I met this friend of mine on 5th of Dec 2010 which was just a causual meeting after 5 years. After having drinks she started touching me and I got aroused and we end up mating. While in act, she... Read more »

Resisting Resistance - A Story

Posted by Survivor, 1 Reply
...wouldn't get much bang out of the NNRTI anyway. In addition, there are suddenly two very new drug classes on the horizon: integrase inhibitors and attachment inhibitors. This would afford me the option of adding them to TMC 114, and having two... Read more »