Indinavir Interaction With Morphine

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Get the Facts

Indinavir (Crixivan)

What Is Indinavir? Indinavir is a drug used as part of antiretroviral therapy (ART). It is also called Crixivan. It is manufactured by Merck & Co. Indinavir is a protease inhibitor. These drugs prevent the protease enzyme from working. HIV protease acts like a chemical scissor. It cuts the raw material for HIV into specific pieces needed to build a new virus. Protease inhibitors "gum up" these scissors. Who Should Take It? Indinavir was...

Ask the Experts

interaction indinavir-buflomedil

Hi.My name is Edgardo Bottaro, I work with HIV-infected patients (I am a physician) and one of them said me that another doctor prebscribed him buflomedil. She receives indinavir since 4 years ago.I think that buflomedil is an unuseful drug, but I...

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine

Buflomedil is not available to my knowledge in the US. It is a adrenergic agonists with some calcium channel blocker activity that is used for intermittent claudication and other indications. I don't know how it is metabolized since I could... Read more »

Delavirdine interactions with Indinavir and other antiretrovirals.

Hi Dr. Cohen!Bob Frascino spoke to a group of us in Monterey, CA last week and began for the first time to explain why I have remained undetectable for so long(4+ years) on the same five drug regimen even though my dosing schedule was not precise....

Response from Cal Cohen, M.D., M.S.

Harvard Medical School

Yup. Very clear. Hope the answer is equally lucid.Yes -- delavirdine (for simplicity I'll abbreviate it DLV) does have similar effects on the p450 system as does ritonavir. Not as potent but similar. So yes you can dose reduce the IDV to... Read more »

Indinavir sulfate

Dear Doctor,I have a question about the dose of Indinavir sulfate.According to a book about HIV/AIDs treatment (Published by POZ organization), the dose of Indinavir is 800mg three time a day and they also put a remark on the dose of this medicine...

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES

Thanks for your post.Indinavir (Crixivan) can be dosed either way-- without ritonavir (Norvir) boosting, the medication is dosed every 8 hours, fasting. Indinavir should not be administered twice daily without ritonavir.With ritonavir, the... Read more »

nelfinavir+indinavir, is it possible?

Nelfinavir+indinavir, is it possible? Nelfinavir+indinavir, is itpossible?...

Response from Cal Cohen, M.D., M.S.

Harvard Medical School

Yes, it's possible. Yes, it's possible. Yes, it's possible.BUT, it hasn't been tested so we wouldn't know what doses to use. Also,since nelfinavir is taken with food and indinavir is taken on an emptystomach, you'd... Read more »

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Widowed Mom

Posted by TeddiC, 4 Replies

I lost my husband to an accidental morphine overdose on Oct 9, 2002. He'd had PCP & cryptococcal meningitis. At the time, I was 2 mos pregnant with our daughter. She was born on May 5, 2003 and is negative. My husband & I were both diagnosed... Read more »

hay caramba!!!! ayudenme

Posted by mariana, 2 Replies

quisiera encontrar lo que dice la OMS sobre el periodo ventana del vih pero no he encontrado ninguna pagina al respecto.Se lo que dice la OMS porque un medico me lo conto... pero me gustaria que peguen algun link en el que la OMS hable del periodo... Read more »

Que opinan de esto?

Posted by Anonymous, 1 Reply

Crecimento rcord de la epidemia mundial de SIDA

Informe. Onusida y la OMS registran en este ao uno de los mayores aumentos en la cifra de personas infectadas con el VIH desde que fue detectado en 1981. Ms de la mitad de las infecciones son de jvenes

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For those on the Atripla regimen

Posted by Pos_in_Thailand

I am giving a URL for a very interesting and complete drug interactions database. If you are on Atripla, and are on or will be needing to take any medication for any reason, you can type it's name in the search and see if there is a known... Read more »

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