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Indinavir Contraindications

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AIDSinfo

An Overview of Crixivan (Indinavir)

... in-DIN-a-veer Brand Name: Crixivan Other Name(s): IDV, Indinavir sulfate, L-735,524, MK-639, Sulfato de indinavir Drug Class: Protease Inhibitors Indinavir sulfate, also known as Crixivan, is a type of medicine called a protease inhibitor (PI). PIs act by blocking protease,
Ask the Experts

switching from indinavir to Lopinavir/r

I have a patient has been well controlled with Indinavr+ AZT+3TC. But now Indinavir is not available. Will it be acceptable to use Lopinavir/r with same 2 NRTIs. The patient had previous exposure to Squinavir also.
Mark Holodniy, M.D., F.A.C.P., C.I.C.

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine
Should not be a problem at all. Read more »

Indinavir sulfate

Dear Doctor,I have a question about the dose of Indinavir sulfate.According to a book about HIV/AIDs treatment (Published by POZ organization), the dose of Indinavir is 800mg three time a day and they also put a remark on the dose of this medicine...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
...Thanks for your post.Indinavir (Crixivan) can be dosed either way-- without ritonavir (Norvir) boosting, the medication is dosed every 8 hours, fasting. Indinavir Read more »

stopping indinavir/ nephrolithiasis

Question 1: my brother is taking azt, ddi, and crixivan, and recently had probable kidney stones, despite drinking large amounts of fluids. What will happen if he discontinues the drug? Can he go on a different protease inhibitor?Or will...
Cal Cohen, M.D., M.S.

Response from Cal Cohen, M.D., M.S.

Harvard Medical School
...Nephrolithiasis (kidney stones) is a potential side effect of indinavir (Crixivan), and although drinking lots of water (at least 2 quarts per day) will lower your chances of developing stones, it Read more »

Delavirdine interactions with Indinavir and other antiretrovirals.

Hi Dr. Cohen!Bob Frascino spoke to a group of us in Monterey, CA last week and began for the first time to explain why I have remained undetectable for so long(4+ years) on the same five drug regimen even though my dosing schedule was not precise. ...
Cal Cohen, M.D., M.S.

Response from Cal Cohen, M.D., M.S.

Harvard Medical School
...does have similar effects on the p450 system as does ritonavir. Not as potent but similar. So yes you can dose reduce the IDV to 600 TID and do well. (not sure why you also have dose reduced the d4T and ddI but I'll leave that one for... Read more »
Articles
The Body PRO

Late Breaker No. LB16: Phase III, Multicenter, Randomized, Open-Label Study to Compare the Antiretroviral Activity and Tolerability of Efavirenz (EFV) + Indinavir (IDV), versus EFV + Zidovudine (ZDV) + Lamuvidine (3TC), versus IDV + ZDV + 3TC at 48 Weeks (Study DMP 266-006)

...counting the events on study. Those who reached PCR    OBS LOCF NC=F EFV/ZDV/3TC 98% 86% 71% EFV/IDV 83% 66% 53% IDV/ZDV/3TC 86% 61% 48% Statistically, there is a difference (p to suppress viral... Read more »
The Body PRO

Poster Session 12359: Durable Clinical Anti-HIV-1 Activity (72 Weeks) and Tolerability for Efavirenz (DMP 266) in Combination with Indinavir (IDV)

...results from which were first presented in San Francisco in September), patients received the protease inhibitor indinavir (IDV, 1000 mg every 8 hours) in combination with the experimental non-nucleoside reverse transcriptase inhibitor efavirenz... Read more »
The Body PRO

Effects of Switching from Saquinivir Hard Capsule (SQV-HC) to Saquinivir Soft Gel Capsules (SQV-SGC) or Indinavir (IDV)

...switching from saquinavirhard capsules (SQV-HC)(1.8 grams/d) to saquinavir soft gel capsules(SQV-SGC) (7.2 grams/d) or indinavir (IDV) (2.4 grams/d), or continuing theSQV-HC. Otherwise, the patients were maintained on their stable nucleosideRTI... Read more »
Test Positive Aware Network

La Guía Annual de Medicamentos para el VIH: Crixivan (Indinavir Sulfate, IDV)

... Nombre de Marca: Crixivan Nombre Común: indinavir sulfate (IDV) Clase: Inhibidor de proteasa (IP) Dosis estándar: Casi nunca se usa sola (dos cápsulas de 400 mg cada 8 horas con el Read more »
Connect With Others

PEP Question

Posted by agny, 1 Reply
...PEP. They didn't favor the idea becasue of all the side effects. Just a question about the prescription. They gave me three: Indinavir Sulfate: every 8 hours Nevirapine: Every 12 hours Abacavir Sulfate: Twice a day Wanted to make sure if there... Read more »

mas efectos del los trataminetos

Posted by Anonymous, 1 Reply
...Retrovir), d4T (estavudina, Zerit), 3TC (lamivudina, Epivir), abacavir (Ziagen), nevirapina (Viramune), efavirenz (Sustiva) e indinavir (Crixivan). Read more »

What do you think?

Posted by Anonymous, 2 Replies
...circulating in the blood] from HIV-seronegative healthy donors with increasing concentrations of IDV [indinavir], SQV [saquinavir], or ddI for 3 days and monitored T-cell proliferation and... Read more »

does your feet and bones hurt too??

Posted by Anonymous
...t-cell was 160 and my viral load was 490,000.00.Now my t-cell is 478 and I'm undectable.I take indinavir,zerit,and lamivudine.Also a number of other PILL'S to help with soreness,dizzyness etc.I get... Read more »