Indinavir And Hiv

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Indinavir (Crixivan)

What Is Indinavir? Indinavir is a drug used as part of antiretroviral therapy (ART). It is also called Crixivan. It is manufactured by Merck & Co. Indinavir is a protease inhibitor. These drugs prevent the protease enzyme from working. HIV protease acts like a chemical scissor. It cuts the raw material for HIV into specific pieces needed to build a new virus. Protease inhibitors "gum up" these scissors. Who Should Take It? Indinavir was...

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indinavir combivir lamivudine in pregnancy

Dear Dr,I would like to ask a very important question.A young collegue of mine registrar in Medicine had an accident with a needle that she used to do a Mantoux to an AIDS patient. She sterted immediately indinavir, combivir and lamivudine. She was...

Response from Brooks Jackson, M.D.

Johns Hopkins University, School of Medicine

The risk of birth defects with antiretroviral therapy appears to be very small with perhaps the exception of Efavirenz (Sustiva). However, there are not a lot of safety data especially with the use of protease inhibitors during early pregnancy so... Read more »

INDINAVIR, NORVIR, LAMIVUDINA

Drs.Iam from Bolivia My brother was diagnosed aids 6 months ago he had only 2 cd4 cells The Dr. is givving him Inidavir, Norvir and lamivudina, do you think this is a good combination or do you think he should try different drugs. What is the...

Response from David Wohl, M.D.

University of North Carolina - Chapel Hill

I suspect your brother is on one more additional drug (probably zidovudine or stavudine) along with his indinavir, ritonavir and lamivudine. If he is not, he should be.This is an older combination of drugs not used much in the US but it should work... Read more »

interaction indinavir-buflomedil

Hi.My name is Edgardo Bottaro, I work with HIV-infected patients (I am a physician) and one of them said me that another doctor prebscribed him buflomedil. She receives indinavir since 4 years ago.I think that buflomedil is an unuseful drug, but I...

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine

Buflomedil is not available to my knowledge in the US. It is a adrenergic agonists with some calcium channel blocker activity that is used for intermittent claudication and other indications. I don't know how it is metabolized since I could... Read more »

Indinavir sulfate

Dear Doctor,I have a question about the dose of Indinavir sulfate.According to a book about HIV/AIDs treatment (Published by POZ organization), the dose of Indinavir is 800mg three time a day and they also put a remark on the dose of this medicine...

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES

Thanks for your post.Indinavir (Crixivan) can be dosed either way-- without ritonavir (Norvir) boosting, the medication is dosed every 8 hours, fasting. Indinavir should not be administered twice daily without ritonavir.With ritonavir, the... Read more »

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