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Increase Reverse Transcriptase Hiv

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AIDS InfoNet

Nucleoside Analog Reverse Transcriptase Inhibitors in Development

These drugs have not been approved by the Food and Drug Administration (FDA) for use against HIV. Nucleoside Analog Reverse Transcriptase Inhibitors These drugs stop HIV from multiplying by blocking the reverse transcriptase enzyme. This enzyme changes HIV's genetic material (RNA) into the form of DNA. This step has to occur before HIV's genetic code gets combined with an infected cell's own genetic codes. The nucleoside analogs (often...
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TESTING for reverse transcriptase

Dear Dr. Conway, As this is a forum for managing side effects of HIV treatment, I was wondering if you can just very quickly answer a question. How do you test for the reverse transcriptase enzyme. Where can you go to be tested for it?Thanks a...
Brian Conway, M.D.

Response from Brian Conway, M.D.

University of British Columbia
This is an experimental test done for research purposes only, in which a DNA/RNA hetrodimer is exposed to the test sample in question (plasma or cell extract) to see if it acts to extend the DNA (a task that can only be accomplished by a reverse... Read more »

Testing for Reverse Transcriptase

Dear Dr. Holodniy, I have a question regarding the enzyme reverse transcriptase. Is the enzyme present in all HIV infections, as well as other retroviruses. If so, how do you test for the enzyme in a patient?Thanks a lot....
Mark Holodniy, M.D., F.A.C.P., C.I.C.

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine
THe enzyme is present in all HIV infections and other retroviral infections. We don't normally test for the RT or RT activity directly. A western blot test, will detect antibodies that have developed against the RT part of the virus. A new test... Read more »

reverse transcriptase

What is reverse transcriptase and how does it work?...
Mark Holodniy, M.D., F.A.C.P., C.I.C.

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine
Reverse transcriptase is an enzyme (or protein) that the HIV virus carries to make a DNA copy of itself once it gets inside a cell. This DNA copy can then get inside the cell nucleus and become incorporated into the human cell DNA. The enzyme takes... Read more »

Reverse Transcriptase Enzyme

Dear Dr. Conway, How are you doing? This isn't the right forum to post my question, but after reading many of your responses and your bio-I truly value your advice. What are some tests that a doctor could run besides the HIV tests that...
Brian Conway, M.D.

Response from Brian Conway, M.D.

University of British Columbia
I would start by saying that the conventional antibody test is very reliable. If the result is negative 6 or more months after a suspected exposure, you can take it for granted that you are NOT infected. In special circumstances, I would confirm... Read more »
Connect With Others

reversing lipodystrophy....

Posted by Anonymous, 1 Reply
Positive since 2003 full blown aids. Was on Kaletra and combivir. Reached non-detectable, and cd4 rising as expected. Into 3rd year noticing increase in truncal girth. Waist went from 27in. to 32in of hard solid protruding fat. Arms, legs, face... Read more »

HIV-1? HIV-2? HIV-O?

Posted by Anonymous, 6 Replies
We didn't even know about HIV until the 1980's. So, we invented a HIV1 test, only to find there is a HIV2. So, we invented a HIV2 only to find out there is a HIV-O. Why are we so ignorant to think there couldn't be another strain...for which we... Read more »

hiv+ Moms w/child

Posted by Anonymous, 1 Reply
Hello,
What medication has the dr put you on? How do you feel? Do you take your medication regularly? How much risk is there in having a baby?
I like to thank you all for your replys in advance!!

Read more »

< 400 copies of HIV RNA per 1 ml of plasma (????)

Posted by Anonymous

PCR RNA @ 28 Days...

Is this a woo-hoo ?
Read more »

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