The Body: The Complete HIV/AIDS Resource
Follow Us Follow Us on Facebook Follow Us on Twitter Download Our App
Professionals >> Visit The Body PROThe Body en Espanol

Immune Reconstitution Inflammatory Syndrome In Hiv

Here's a taste of what has to offer on this topic:
Get the Facts
The Well Project

Immune Reconstitution

...Restoration Syndrome Although an increase in CD4 cell counts is a good sign, it has led to aflare up of certain types of infections or a worsening of these infections insome HIV+ people. This is referred to as immune restoration inflammatorysyndrome (IRIS). The reported infections include Mycobacterium avium complex (MAC), cytomegalovirus (CMV), herpes simplex virus, hepatitis B and C,tuberculosis (TB), and herpes zoster (or shingles). ...
Ask the Experts


I found out I am HIV positive on July 9,2007 and was put on Atripla. It has been working great for me, but every since I have started taking it I have had rashes come and go on my feet and ancles. Some of them are open to where I have to put a...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine your feet. Sometimes those flare up after starting effective HIV medication (part of the spectrum of immune reconstitution inflammatory syndrome or IRIS). I would have your HIV specialist check your feet out. I often refer patients with a skin... Read more »

Prednisone and IRIS

I developed Immune Reconstitution Inflammatory Syndrome(IRIS) after starting HIV Med 8 months ago. Hospitalized shortly until diagnosed with IRIS in my intestines. I started with 40mg of prednisone daily and am down to 20mg. Can't seem to get much...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
...Most patients have little immune suppression on 10 mg prednisone but it tends to increase with higher doses. Use of prednisone can lead to secondary adrenal insufficiency Read more »

schizophrenia and HIV/AIDS diagnosis late stage

we recently found my son who has been missing for 3 years. he has schizophrenia which ia 1 reason why we could not find him. He is 31 and has been in the streets. I got a call from harborview and they had him in because he had collapsed and needed...
Nelson Vergel, B.S.Ch.E., M.B.A.

Response from Nelson Vergel, B.S.Ch.E., M.B.A.

Program for Wellness Restoration
...also takes Bactrim if he is not allergic to it to prevent PCP pneumonia. Keep an eye on any potential immune reconstitution inflammatory syndrome : this article about diet which has great... Read more »

IRIS - immune reconstitution inflammatory syndrome

Gerald Pierone, M.D.

Response from Gerald Pierone, M.D.

AIDS Research and Treatment Center of the Treasure Coast
... Hello and thanks for posting. IRIS is the acronym for immune reconstitution inflammatory syndrome and based on the description of events in your post it seems to fit your situation. Here is a link to some Read more »
AIDS InfoNet

Immune Restoration Syndrome

...problems usually occur in the first two months after starting HIV therapy. This condition is sometimes called Immune Restoration Inflammatory Syndrome or IRIS. It may occur in about 20% of people starting ART. How Was the Syndrome... Read more »
San Francisco AIDS Foundation

Inflammation, Immune Activation and HIV

...The resulting inflammatory cascade releases "downstream" molecules such as CRP that can be measured in circulating blood. The inflamed endothelial lining around these lesions expresses adhesion molecules -- including VCAM-1, ICAM-1, and... Read more »
San Francisco AIDS Foundation

Immune Reconstitution Syndrome

... Syndrome Identified Conditions Associated With Inflammatory Reactions Mechanism of Action Incidence Risk Factors Management Grounds for Optimism Selected Sources Immune Read more »
Project Inform

IRIS: A Concern for People Starting HIV Therapy

... Introduction What Is Inflammation? What Is IRIS? How Is It Diagnosed? Who Is at Risk? What Are the Symptoms? How Do You Treat IRIS? What Read more »
Connect With Others

Hiv+ for 20yrs/No meds having night sweats/rash

Posted by ajpooboy, 5 Replies
I am a white male Nordic background and have never been sick.I have never been on Meds ever. Been Poz for 20+ yrs but now am having night sweats/day sweats and have developed a rash all over my body. Mt CD4 has always been around 600 and my VL... Read more »

News 4 HIV'ers

Posted by AIDS2HIV, 3 Replies
...over-activity of the thyroid gland. The investigators believe that the disease should be considered an immune reconstitution inflammatory syndrome (IRIS) autoimmune disease. Four of the five cases described by the investigators from the United... Read more »

Immune system & HIV detection

Posted by andypb, 1 Reply
...What is compromised/ supressed immune system. Does compromised/ weak immune system take more time to produce antibody to HIV infection. Would a Person having as Read more »

Boyfriend just diagnosed

Posted by Tori, 4 Replies
...On Halloween, my boyfriend's preliminary HIV test came out positive and it has since been confirmed by some other test. We are a mongamous couple who only used protection Read more »