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How To Prevent Wasting When You Are Hiv Positive

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AIDS InfoNet

Wasting Syndrome

Hormone levels can affect the metabolism. HIV seems to change some hormone levels including testosterone and thyroid. Also, cytokines play a role in wasting. Cytokines are proteins that produce inflammation to help the body fight infections. People with HIV have very high levels of cytokines. This makes the body produce more fats and sugars, but less protein. Unfortunately, these factors can work together to create a "downward spiral." For...
Ask the Experts

Best drug treatments to prevent facial wasting

Im a 43 year old male who became HIV positive 24 months ago. I just started taking HIV medications when my CD4 count dropped to 500 and viral load increased to over 17,000. My doctor put me on Truvada and Sustiva for 6 months now and my CD4 count is...
Gerald Pierone, M.D.

Response from Gerald Pierone, M.D.

AIDS Research and Treatment Center of the Treasure Coast
Hello, and thanks for posting. I am not aware of any studies that show less lipoatrophy with Isentress compared with Sustiva. There would probably be less risk of lipoatrophy with Kaletra, but the trade off would be more side effects and greater... Read more »

weight wasting being an adolescent hiv positive

My daughter is 17 and a year has passed since she began wasting weight. Now she weights 37 kg. We are from Argentina, Ive tried many psychological therapies with no result. My daughter is constantly depressed and deserts every treatment we start. Im...
Ewald Horwath, M.D.

Response from Ewald Horwath, M.D.

University of Miami School of Medicine
The wasting is not a psychological symptom. In most people with HIV infection, it is a biological manifestation of caused by some of the chemicals released by the inflammatory response that the virus causes. You should consult her doctor for advice... Read more »

How best to prevent facial wasting after treatment interruption?

I have been on a drug "holiday" for the past 18 months, after 12 years of HIV therapy. I stopped my meds with high CD4 count of 1100 and undetectable viral load. The reason I stopped therapy was because, even though I felt great, I had...
Gerald Pierone, M.D.

Response from Gerald Pierone, M.D.

AIDS Research and Treatment Center of the Treasure Coast
Hello, and thanks for posting. You do not seem vain and asking to take an effective regimen with the lowest chance of lipoatrophy is a perfectly reasonable request. It would be important to know what your regimen was before the treatment... Read more »

Alternatives to d4T to prevent facial wasting?

I was recently diagnosed with HIV, and am starting combination therapy. I am very concerned about facial wasting. d4T was mentioned as a part of the proposed combination therapy, but I know it is considered as a possible contributor to facial...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
The direct role of D4T regarding facial wasting is still under study. There usually is not much of a problem for the first several years one is on therapy (even with D4T). If a problem develops early then one can switch off a drug(s) that could be... Read more »
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