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How Often Do You Have To Take Maraviroc

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Get the Facts
AIDS InfoNet

Maraviroc (Selzentry, Celsentri)

What Is Maraviroc? Who Should Take It? What About Drug Resistance? How Is Maraviroc Taken? What Are the Side Effects? How Does It React With OtherDrugs? The Bottom Line What Is Maraviroc? Maraviroc (Selzentry in the US and Celsentri elsewhere) was formerly known as UK 427,857. It is a drug used for antiretroviral therapy. It is manufactured by ViiV Healthcare. Maraviroc is the first "attachment inhibitor" drug. ...
Ask the Experts

Atripla and Maraviroc

Dear Docters,I was hoping to put a question before you as I am about to start first line treatment soon (my CD4's range between the 400 and 450, CD4/CD8% is 23, VL 16.000).My doc suggested to start with Atripla AND temporarly Maraviroc. He calls it...
Joseph McGowan, M.D., F.A.C.P.

Response from Joseph McGowan, M.D., F.A.C.P.

North Shore University Hospital
Dear ThomT:There is no harm in having too fast a drop in viral load. Some studies indicate that the faster the decline in viral load, the more durable the response may be. Of course, this is dependent on continuing to take your meds without... Read more »

Maraviroc

My viral load has become detectable and my doctor would like to put me on Maraviroc and Isentress. I have been reviewing both of these drugs and I have some concerns with Maraviroc. I know it works on the CCR5 but what is known about the CCR5...
Joseph McGowan, M.D., F.A.C.P.

Response from Joseph McGowan, M.D., F.A.C.P.

North Shore University Hospital
The CCR5 receptor is a receptor on the CD4 T cell. It is used as a 2nd (or co-) receptor for HIV to enter the T cell. HIV may also use another co-receptor (called CXCR4) to enter the cell. Since maraviroc only blocks virus that use CCR5, it is... Read more »

maraviroc

hi drgood morninghope all is well on your side.i am a male of 30 newly diagnosed with hiv during a blood donation camp.in couple of days my lab results for cd4 and viral load will be out and i will see an hiv specialist for the drug regimen.i read...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
There is comparativey little info about use of CCR5 inhibitors like maraviroc for initial treatment of HIV infection. Since the success rates for initial therapy with current often simple (once daily ) regimens is now fairly high (often > 90%)... Read more »

Maraviroc, Isentress & Atripla?

It is time to change meds. My t-cells are down to 203 (12%) but I have a low, but measurable viral load (500 or so). I have the 69-insertion mutation, so nuks don't work - but I am sensitive to all other classes. I also am CCR5- tropic. I have...
Edwin DeJesus, M.D., F.A.C.P.

Response from Edwin DeJesus, M.D., F.A.C.P.

Auchhh some how this story is not adding up well. If you have never taking a PI or an NNRTI, I assume that you were treated in the past only with nucleosides! That was not an acceptable treatment. If you developed the insertion 69, I also have to... Read more »
Articles
AIDSinfo

An Overview of Selzentry (Maraviroc, Celsentri)

mah-RAV-er-rock Brand Name: Selzentry Other Name(s): Celsentri, MVC, UK-427,857 Drug Class: Entry and Fusion Inhibitors Maraviroc, also known as Selzentry, is a type of medicine called an entry inhibitor. Entry inhibitors work... Read more »
InfoRed SIDA

Maraviroc (Selzentry, Celsentri)

¿Qué Es Maraviroc? ¿Quién Debe Tomar Maraviroc? ¿Qué Es la Resistencia a los Medicamentos? ¿Cómo se Toma Maraviroc? ¿Cuáles Son los Efectos Secundarios? ¿Cómo Reacciona Maraviroc con Otros Medicamentos? En Pocas... Read more »
British Columbia Centre for Excellence in HIV/AIDS

Genetic Test Predicts Response to Maraviroc in Treatment-Experienced HIV Patients

Vancouver, British Columbia, Canada -- A genetic approach to determining HIV tropism can be used to effectively identify patients who will respond to treatment with the CCR5 antagonist maraviroc, according to new data presented today at the 5th... Read more »
U.S. Food and Drug Administration

Traditional Approval and Label Changes for Selzentry (Maraviroc)

On November 25, 2008, FDA granted full, traditional approval for the use of maraviroc in treatment-experienced patients infected with CCR5-tropic HIV-1. The change from accelerated to traditional approval was based on 48 week data from two... Read more »
Connect With Others

chicago,il. Alguien sabe de alguna cura para vih?

Posted by adriana, 3 Replies
hola, mi nombre es adriana y auque tengo viviendo con el virus 4 anios en realidad no tengo mucha informacion creo q por no querer pensar demaciado en este virus lo hice a un lado, claro sin dejar de cuidarme. me gustaria saber si alguien de ustedes... Read more »

Entry Inhibitors

Posted by Anonymous, 1 Reply
Does anyone know anything about the new entry inhibitors? I think Pfizer and Schering both have drugs in development. Should we be hopeful? Read more »