How Much Does Zidovudine Cost

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Zidovudine (Retrovir, AZT)

What Is Zidovudine? Zidovudine (Retrovir) is a drug used for antiretroviral therapy (ART). It was first manufactured by GlaxoSmithKline. It is manufactured by ViiV Healthcare. The patent on zidovudine expired in 2005 and several generic versions have been approved. Several are available under PEPFAR (see Fact Sheet 475 ). Zidovudine is also known as azidodeoxythymidine, AZT or ZDV. Zidovudine was the first drug approved for the treatment of...

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Switch from Zidovudine

My wife with a baseline CD4 of 83 (12.8%), and viral load of 2071 is on Zidovudine, Lamivudine, and Nevirapine for 6 weeks. She is also taking Bactrim DS for 2 weeks. While she has tolerated the drugs, she has recently reported a decline in white...

Response from Brian Conway, M.D.

University of British Columbia

You ask a very analytical question. Your doctor is right in that the combination of Bactrim and zidovudine may be particularly bad for the white blood cells, especially in someone who is deficient in folate. Sometimes, before making any changes in... Read more »

developed lipoatrophy while on videx,zidovudine and aluvia

what is lipoatrophy(from 2006 on videx and zidovudine) and can it be treated and how but i'm now switched to truvada and aluvia after alerting my doctor about my fat distribution last month ...

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine

Fat loss (lipoatrophy) and fat gain have been linked to zidovudine and somewhat less so to didanosine (Videx). Switching to Truvada and Aluvia (lopinavir/ritonavir) may stabilize the fat loss with slow recovery. Its impact on areas of fat gain is... Read more »

zidovudine

under which of the following conditions is azt (zidovudine) prescribed for patients suffering from hiv?...

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES

Zidovudine (AZT, Retrovir) is used as part of combination therapy for the treatment of HIV-infected individuals or in special circumstances for the prevention of HIV infection, following high-risk exposure. BY... Read more »

infant zidovudine: recommendations for dose escalation with weight gain?

I know standard dosage for zidovudine for an infant born to an HIV positive mother is "2 mg/kg body weight q6h" as part of the MTCT prevention. In 6 weeks time however, an infant easily weighs a kilo, to 1.5 kg more which is up to 50% of...

Response from Katherine Luzuriaga, M.D.

University of Massachusetts, Medical School

In our clinic, we usually see babies at 1 and 4 weeks to see how things are going, check their weights, and to draw bloods to check for infection. If weight is increased by more than 10% of the baby's previous weight, we adjust the dose. If... Read more »

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