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How Much Do Protease Inhibitors Cost

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AIDS InfoNet

Protease Inhibitors in Development

These drugs have not been approved by the Food and Drug Administration (FDA) for use against HIV. Protease Inhibitors These drugs block the protease enzyme. When new viral particles break off from an infected cell, protease cuts long protein strands into the parts needed to assemble a mature virus. When protease is blocked, the new viral particles cannot mature. Protease Inhibitors in Development Several firms are trying to develop a new...
Ask the Experts

Do protease inhibitors cure or just postpone?

I have read several of you're articles and would be extremely grateful if you could answer a few questions. First, do you feelHMO's and other managed care organizations should include such treatments as protease inhibitors in there plans?...
Cal Cohen, M.D., M.S.

Response from Cal Cohen, M.D., M.S.

Harvard Medical School
First, let me answer the question you posed in the title of your question: do protease inhibitors cure HIV disease or delay progression? We know that all antiretroviral therapy delays progression (and death), and that the more effective the... Read more »

Protease inhibitor funding in New Zealand

The NZ government is currently holding off making protease inhibitors available to people with HIV. They claim that thedrugs merely stave off the onset of Aids and death, rather than providing any sort of long-term benefit. What evidence wouldyou...
Cal Cohen, M.D., M.S.

Response from Cal Cohen, M.D., M.S.

Harvard Medical School
I don't want to get into a fight with the government of New Zealand, as it's a place I very much hope to visit someday. I will just make a few comments: Protease inhibitors have been shown to decrease the complications associated with... Read more »

Injectable Protease Inhibitors

Given the gastronitestinal side effects that make protease inhibitors so unpleasant shouldn't there by an injectable option/formulation to bypass the stomach? Fuzeon has problems too, but many people do well for years injecting that or insulin....
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
Your point is well taken though there are costs and side effects associated with the subcutaneous injection route as well. We have had some patients in whom we have put in a percutanous feeding tube from the skin to the stomach or small bowel to... Read more »

Necessity to do Viral Loads before Rxing aProtease Inhibitor

Viral Load testing is very expensive, therefore a number of persons unable to pay or not in a position to make certain freedecissions about there health care are not getting perscribed Protease Inhibitors due to the cost factor of the test. Is it...
Cal Cohen, M.D., M.S.

Response from Cal Cohen, M.D., M.S.

Harvard Medical School
I'm glad you're concerned about this issue. Let me try to give you some ammunition to further your cause.A viral load is about $200, max. If done four times per year, that's $800. Protease inhibitors run around $5000 - $7000 per... Read more »
Connect With Others

lipodystrophy from protease inhibitors

Posted by Anonymous, 4 Replies
I have known about my HIV+ status now for 6 years, and God has blessed me with continued good health. I have accessed all the major medications, plus vitamins to help fight the disease. Once I started taking the new protease inhibitors, I started... Read more »

bone density loss due to protease inhibitors

Posted by Anonymous, 1 Reply
Curious as to latest info. on research into bone density loss due to HAART therapy. Most research data i've seen goes back to 99 or 2000. Any new data/research into this? Also any info. on clinical trials currently under way looking into this... Read more »

Hyperglycemia as a result of Protease Inhibitors

Posted by Anonymous
I found a product for reducing glucose levels. It is called Meishan Tea. They make 4 different kinds of tea and I have people that are showing tremendous results on all 4 kinds. However, the people that are presently taking the tea do not have AIDS.... Read more »

Protease Inhibitors - Hemophilia bleeds

Posted by akcol
Hi, my fiance is a Long Term NonProgressor - 24 years positive, co-infection HCV, with severe Hemophilia A.

This is a question for the gentlemen with Hemophilia please.
We're requesting any input about any Hemophilic PI increased unusual bleed... Read more »