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How Long Does It Take Hiv To Infect A Cell

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AIDS InfoNet

CD4 Cell Tests

...T-8 cells (CD8+) are "suppressor" cells that end the immune response. CD8 cells can also be "killer" cells that kill cancer cells and cells infected with a virus. Researchers can tell these cells apart by specific proteins on the cell surface. A T-4 cell is a T-cell with CD4 molecules on its surface. This type of T-cell is also called "CD4 positive," or CD4. Why Are CD4 Cells Important in HIV? When HIV infects humans, the cells it...
Ask the Experts

CD4 cell lifespan with and without treatment

Dear Dr. I'm just curious about the lifespan of a cd4 cell in a person who is hiv negative and a person who is hiv positive with and without treatment. What's the average # of days these cells can live?; and, is there a difference between an hiv...
Mark Holodniy, M.D., F.A.C.P., C.I.C.

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine
...This is a hard question to answer. Some CD4 cells only survive a few days and some potentially months to years, as CD4 cells are not uniform in nature and represent a family of Read more »

Isolation of a cellular factor that can reactivate latent HIV-1 without T cell activation.

What do you think of the research of Siliciano and Pomerantz ? HIV-1 latency in resting CD4+ T cells represents a major barrier to virus eradication in patients on highly active antiretroviral therapy (HAART). Eliminating the latent HIV-1 reservoir...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
...Hello and thanks for your post.It's a very long way from early clinical science to a drug, never mind being "very close to the cure". Even for less revolutionary discoveries, Read more »

HIV % and drop in T-Cell

I have been HIV+ for about 12 years, and have been a long-term non-progresser. I have never been on meds. My t-cell normally runs from the high 500-900. And my viral load is under 1000. I get checked in 6 month intervals. My last blood work showed...
Mark Holodniy, M.D., F.A.C.P., C.I.C.

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine
...You don't indicate what the CD4 percent has been doing all along, and whether it has always been around 32% or it was lower. However, given the number of years you have been infected and the Read more »

Resting Cells

Hi, I'm a medical student studying in the uk and i'm hoping you can help me clear up a rather confusing question. hiv when it enters the body targets cd4 t cells of which they can be active or resting, enters the cells and incorporates itself into...
Joseph McGowan, M.D., F.A.C.P.

Response from Joseph McGowan, M.D., F.A.C.P.

North Shore University Hospital
...Dear Andy,Thanks for your question and good luck with your studies. You raise an escellent point.While HIV preferntially infects activated CD4 cells, it can also infect resting cells. It is the long-lived memory cells in the resting Read more »
Articles
U.S. Centers for Disease Control and Prevention

Incomplete Peripheral CD4+ Cell Count Restoration in HIV-Infected Patients Receiving Long-Term Antiretroviral Treatment

... In most HIV-positive patients, antiretroviral therapy can fully restore a normal CD4+ cell count of more than 500 cells/mm 3 . However, the researchers note, it is not clear whether all patients can achieve normalization of their CD4+ cell count, Read more »
National Institute of Allergy and Infectious Diseases

Well-Armed Immune Cells Help Long-Term Non-Progressors Contain HIV

...by the CD8+ T cells punches holes in the infected cells. Then a second protein, granzyme B, penetrates those holes and causes the cells to die. Previously, the researchers found that HIV-specific CD8+ T cells of progressors, unlike those of... Read more »
U.S. National Institute of Allergy and Infectious Diseases

HIV Selectively Suppresses Anti-HIV Defense Cells

...therefore exposed to more of the virus than are cells that fight other pathogens. To test this hypothesis, the researchers examined the cells of four HIV-positive individuals undergoing structured treatment interruption of their antiretroviral... Read more »
AIDS InfoNet

Acute HIV Infection

... What Is Acute HIV Infection? Testing for Acute HIV Infection Risk of Immune Damage Risk of Infecting Others Treating Acute HIV Infection Read more »
Connect With Others

Worried..T-Cells count going down fast!

Posted by Overstressed, 4 Replies
...what to expect..I started @1041 T-Cell and viral load 45,000 and of course I would go in and get my count every 3 months . My T-Cells would be droping so fast and in times it would be up again . There would be times that I would have 510 T-Cell... Read more »

Scientists Discover 'Natural Barrier' to HIV

Posted by MOCHA
...Langerhans cells from 13 human donors, may explain why. When HIV comes in contact with genital mucosa, its ultimate target -- the cells it seeks to hijack and destroy -- are immune system T-cells. But T-cells are relatively far away (in lymph... Read more »

See,I told you HIV replicates a cell's DNA TO RNA

Posted by Anonymous, 1 Reply
...However, the problem is not free virus, but the fact that the viral RNA has become incorporated into the DNA of CD4 cells and other human cells. As long as those cells are alive, the virus is safe and capable of ... Read more »

How Soon Should T-Cell Count Increase?

Posted by Anonymous, 5 Replies
...originally 318 when I was diagnosed and it has only gone up to 340 after the same period of meds treatment. Is it normal for T-cells to take that long to recover/increase when my viral load seems to be doing so well/coming down so fast? Anyone... Read more »