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How Long Does D4T Take To Work

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AIDSinfo

An Overview of Zerit (Stavudine, d4T)

STAV-yoo-deen Brand Name: Zerit Other Name: d4T Drug Class: Nucleoside Reverse Transcriptase Inhibitors Approved Use: Treatment of HIV Infection WARNING: Stavudine can cause serious, life-threatening side effects. These include lactic acidosis (build up of acid in the blood), liver problems, and pancreatitis (inflammation of the pancreas). Contact your health care provider right away if you have any of the...
Ask the Experts

Viagra works with 3TC+D4T+Sustiva?

To start, thanks for your help!! I have had ED after some years and I had been trying Viagra to avoid this kind of trouble. I started using Viagra(25mg) when I was using 3TC+D4T+Crixivan and it was very fine... Full and long erection.... Now,...
Brian Boyle, M.D., J.D.

Response from Brian Boyle, M.D., J.D.

Cornell University, Weill Medical College
While a Viagra/Sustiva interaction is not specifically listed in either package insert, Sustiva induces the enzymes (CYP3A4 and 2C9) that metabolize Viagra, and therefore, it is likely that concomitant use of Sustiva and Viagra may reduce, to some... Read more »

dropping D4T and initiating a PI.

Hi, My question is this: I'm a long-term nonprogressor of 15 years currently on zerit, viramune, and abacavir. I have had neuropathy in my feet/legs and hands. My Dr. wants to remove the zerit (a known cause of peripheral neuropathy) and add...
Cal Cohen, M.D., M.S.

Response from Cal Cohen, M.D., M.S.

Harvard Medical School
Hey Jim. Here are the current issues -- there are 5 PI's now to choose from as single drugs, and then lots more choices when using them together. None of them have any neuropathy as a side effect, so any of them are reasonable choices for... Read more »

Hair Loss - Most Likely Culprit D4T or Sustiva

I know you may not really be able to answer this question - but here goes anyway.I was previously on a comb including D4T & Sustiva - hair loss (scalp) within 3-4 wks of starting comb - achieved good results u/det rising CD4'sHad a long...
Brian Boyle, M.D., J.D.

Response from Brian Boyle, M.D., J.D.

Cornell University, Weill Medical College
The literature does not indicate that there is any association of d4T with hair loss. Sustiva has been associated with alopecia (hair loss) in some patients, but that is very uncommon. We use these medications frequently and have not run into a... Read more »

Substitute AZT for D4T in treatment experienced?

My doctor told me today that more recent studies now suggest that AZT really has very much the same resistance profile as D4T. Is this true? The reason I ask is that I have been on D4T, DDI and Sustiva for the past two years (with no detectable...
Susan Little, M.D.

Response from Susan Little, M.D.

University of California San Diego
Well - you have raised a lot of good questions and I will try to answer then in order:1. d4T and AZT do select for some of the same resistance mutations. They are not completely overlapping, but there are several common mutations that could be... Read more »
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My girlfriend watched a video in school saying that it could take ten years, while testing every five months, to determine if you have AID's. Is there any truth to that? Read more »

RE:how long meds work

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How long does it take for meds to work?

Posted by Anonymous, 3 Replies
After one month on HAAART my loved ones counts are, in comparison to 100000 viral load and cd of under 20, the viral load is now 325 and cd4 is 35. I've heard it takes 3-6 months to get the viral load undetectable and longer to get the cd4 back over... Read more »

MORE Good News! THERAPEUTIC VACCINE IS WORKING!

Posted by Anonymous, 2 Replies
Dr. David Ho: "It's terrific. I would say full speed ahead for this particular research program."

The results "are extremely encouraging and what many of us had hoped we's see when the trial started," echoed Dr. Robert Schooley.

"There's still a long... Read more »