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How Long Does Tenofovir Take To Work

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Get the Facts
AIDS InfoNet

Tenofovir (Viread)

What Is Tenofovir? Tenofovir (Viread), also called bis-POC PMPA, is a drug used as part of antiretroviral therapy (ART). It is manufactured by Gilead Sciences. The FDA approved tenofovir for use against HIV in October 2001. Generic versions have been tentatively approved under PEPFAR (see Fact Sheet 475 ). Tenofovir is a nucleotide analog reverse transcriptase inhibitor, or nuke. These drugs stop HIV from multiplying by preventing the reverse...
Ask the Experts

Combivir & Tenofovir

Hi, I've been taking Combivir and Tenofovir for 3 years as my first combination. It seems to work for me, viral load below 50 and CD4 count of 700+ for virtually all that time. My Consultant mentioned they dont use this as a first combination...
Gerald Pierone, M.D.

Response from Gerald Pierone, M.D.

AIDS Research and Treatment Center of the Treasure Coast
Several years ago multiple studies were done with different triple nucleoside regimens and most of them demonstrated underperformance compared with NNRTI-based HAART. Interestingly, there were some small studies of Combivir and tenofovir (Viread)... Read more »

Switching from AZT to Tenofovir?

Thank you for providing this excellent source of HIV info.I am a 46 yo male, have been taking AZT, 3TC, and Sustiva for 18 months. VL is undetectable, CD4 28% 415, I feel healthy and exercise regularly. No sign of lipo-atrophy either. However...
Eric Daar, M.D.

Response from Eric Daar, M.D.

UCLA School of Medicine
Thank you for your post.The important thing to note is that you are doing great and in all likelihood will continue to do so as long as you take your medications consistently. At this point the decision to make a change is very much a personal one... Read more »

T20 + Tenofovir + What?

Dear Dr. Cohen,This is P in B town -- we met when you came here for the Teaching Day earlier this year. Well, after 11 years of drug therapy, my last readily available salvage therapy of DLV/AGN/ZGN has gone belly up. My CD4 has dropped in half to...
Cal Cohen, M.D., M.S.

Response from Cal Cohen, M.D., M.S.

Harvard Medical School
Hi P. As you can see I've posted your note with the identifiers removed... in case you didn't want worldwide publicity just yet...Tough situation. Tenofovir has some potency in this circumstance - on average about 0.6 logs. So enough... Read more »


HelloIve been positive since 1997. I have struggked with treatments in terms of side effects.For example, I get anemia with AZT, and Peripheral Neuropathy with D4t.For a long time I took Crix, 3tc and Nevirapine. This worked well, with Cd4s over 100...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
Switch options are heavily dependent on what drugs are available to you and what resistance pattern exists for your strain(s) of HIV. Sometimes switching to a protease inhibitor other than lopinavir (ie atazanavir, saquinavir. fosamprenavir, or... Read more »
Connect With Others

HIV testing while on tenofovir.

Posted by EmeandEme, 1 Reply
I have been taking tenofovir for over 6 months for Hep B. 3 months ago I had unprotected sex because the condom broke and need to figure out what test I need to take to check for HIV.

I have gotten tested every single month and everything has come... Read more »

How long should I wait for testing to work?

Posted by Anonymous, 4 Replies
My girlfriend watched a video in school saying that it could take ten years, while testing every five months, to determine if you have AID's. Is there any truth to that? Read more »

RE:how long meds work

Posted by Anonymous, 2 Replies
Hi pals. I was wondering if anyone on the regimen: Viracept+Combivir has any idea how good this regimen is. I want to know what's the average period of time some of you have been on these meds for. I've been taking them for about 7 months and on... Read more »

How long does it take for meds to work?

Posted by Anonymous, 3 Replies
After one month on HAAART my loved ones counts are, in comparison to 100000 viral load and cd of under 20, the viral load is now 325 and cd4 is 35. I've heard it takes 3-6 months to get the viral load undetectable and longer to get the cd4 back over... Read more »