How Long Does Stavudine Take To Work

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Stavudine (Zerit)

What Is Stavudine? Stavudine (Zerit) is a drug used as part of antiretroviral therapy (ART). It is manufactured by Bristol-Myers Squibb. The original patent on stavudine has expired. The U.S. Food and Drug Administration (FDA) approved generic forms of stavudine for sale in the U.S. and under PEPFAR (see Fact Sheet 475 ). Stavudine is also known as d4T or didehydro-deoxythymidine. Stavudine is the most commonly used anti-HIV medication...

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Concerns about long time Stavudine use in a child

My son was diagnosed with AIDS in 1/20/04. As of 6/2004, he has been on a regimen of Stavudine, Lamuvidine and Kaletra. I am concerned about the long term effects of Stavudine. Are there better combinations? Are we going to be sorry that he stays...

Response from Gerald Pierone, M.D.

AIDS Research and Treatment Center of the Treasure Coast

In adults there has been a unmistakable shift away from using stavudine (Zerit) towards tenofovir (Viread). One of the main reasons for this change is that Viread has a better side effect profile and can be given once daily. The changes in... Read more »

Stavudine toxicity

what can used in conjuction with lamivudine, stocrin in place of stavudine?What do we need to do to prevent pre-mature aging of body cells?...

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine

If available and depending on the nature of the problems with stavudine, it is most often switched to tenofovir or abacavir (if HLA B5701 negative or low risk for hypersensitivity reactio) or ziduvudine. Avoiding premature aging in the setting of... Read more »

Stavudine (Zerit) once a day?

HiI am in the UK, I started on meds nearly a year ago - sustiva once a day, epivir twice a day and stavudine (zerit) twice a day. My VL is down from over 100,000 to undetectable and cd4 count up from 245 to just under 500.I am keen to get onto...

Response from Sharon Lee, M.D.

University of Kansas Medical Center

The BristolMeyerSquibb company representatives have told me there is currently no specific release date set for the once daily capsules. The company has been working on this for some time, and I am relatively certain it will be available sometime in... Read more »

neuropathy pain (didanosine+stavudine+efavirenz)

Dear Dr Robert J. Frascino, I'm sure many patients email you a lot of times regarding this matter. But I really really hope you won't get bored. I'd really really appreciate your help, time and patience!My question is:My father CD4...

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation

Hi Tom,Didanosine (ddI) plus stavudine (d4T) is no longer a recommended combination! It has been found to be less effective and substantially more toxic than many other nucleoside combinations, such as AZT/3TC or Viread/FTC, for example. The ddI... Read more »

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