How Long Does Saquinavir Take To Work

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Get the Facts

An Overview of Invirase (Saquinavir mesylate)

sack-KWIN-uh-vihr MEH-sih-LATE --> Brand Name: Invirase Other Names: SQV, saquinavir mesylate Drug Class: Protease Inhibitors Approved Use: Treatment of HIV Infection WARNING: Saquinavir can cause serious, life-threatening side effects. These include heart rhythm problems and liver problems. Contact your health care provider right away if you have any of the following symptoms that may signal heart rhythm problems: ...

Ask the Experts

start with saquinavir?

My husband has a CD4=270 and viral load=5000.He was on AZT/Ddc for a year which achieved those numbers andsustained them.His Dr. felt it should be lower and tried AZT/DDi/nevaripine lastmonth and he had a bad reaction to thenevaripine after 2...

Response from Cal Cohen, M.D., M.S.

Harvard Medical School

I don't use saquinavir as a sole protease inhibitor, myself, for reasons that I've discussed before: it achieves poor serum levels and is therefore less effective than other protease inhibitors, and it may promote partial (not complete)... Read more »

High Dose Saquinavir

Dear Dr. Gallant, Currently on azt,3tc, and 7200mgs/day saq. Thinking ofswitching to Crix. If Saq is still working wouldyou suggest this or not? Also what is your opinion of high dose saq? Iffailure occurs do you recomend changing one or alldrugs in...

Response from Joel Gallant, M.D.

Johns Hopkins University, School of Medicine

If your viral load is undetectable on the current regimen, there'd be nothingwrong with sticking with it, unless the change involved adding ritonavir ornelfinavir, which increase saquinavir levels.If your viral load is detectable, then... Read more »

How long do newer regimes work?

Hello,first many thanks for your work, this site and especially the questions and answers helped me much since diagnosis. I just wanted to ask how long newer regim work on average for treatment naive patients? Thanks ...

Response from Gerald Pierone, M.D.

AIDS Research and Treatment Center of the Treasure Coast

Well, that depends on the patient. For someone that has perfect adherence and no medication related side effects, they will work indefinitely. For someone with very poor adherence they don't work very well at all. For someone with mediocre... Read more »

how long meds work

dr cohen how long do the meds work? im hiv positive. my dr tells me i can live a full life as long as i adhere to my medications. my viral load is undetectable. my friend who is also hiv positive tells me that the meds only work for 10 years or...

Response from Cal Cohen, M.D., M.S.

Harvard Medical School

Well, it kinda depends on two things - #1; whether you're an optimist or a pessimist, and #2; how good I am at predicting the future. So, here are the issues.It is clear that about 5 years ago, with the principles we now use for treatment,... Read more »

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How long does it take for meds to work?

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Med resistance on Norvir/Saquinivar..anyone else?

Posted by Anonymous, 1 Reply

I have been on Norvir/Saquinavir for 7 years. Starting to show resistance. Panicking a little, they worked for so long,
controlled side effects. Doctor wants to do labs more frequently for now but not switch, maybe add another drug.
Has anyone gone... Read more »

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