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How Long Does Saquinavir Take To Work

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Get the Facts
The Well Project

HIV Drugs and the HIV Lifecycle

... Protease Inhibitors (PIs) These drugs interfere with HIV's protease enzyme. There are many approved PIs: Aptivus (tipranivir) Crixivan (indinavir) Invirase (saquinavir) Kaletra (lopinavir plus ritonavir) Lexiva (fosamprenavir) Norvir (ritonavir) Prezista (darunavir or TMC-114) Reyataz (atazanavir) ...
Ask the Experts

Viracept/Saquinivir ALWAYS better than justViracept?

Dr. Gallant: In a couple of your answers you've said that Viracept (as well as Ritonivir) greatly strengthens the otherwiseweak Saquinivir against HIV in combo therapy with nukes. My boyfriend just got d4T/3TC +Viracept prescribed to him ashis...
Joel Gallant, M.D.

Response from Joel Gallant, M.D.

Johns Hopkins University, School of Medicine
...Nelfinavir (Viracept) does not "greatly strengthen" saquinavir (the way ritonavir does), but it does modestly enhance saquinavir levels. While with ritonavir you can take reduced doses of Read more »

First meds

I have recently been put on Truvada - one daily, Ritonavir 100mg - once daily and Darunavir 300mg - 3 tabs once daily. Blood results just before commencing medication CD4 302 (13.7%) and Viral Load 14 667. I have been + for 12 years and only took...
David Wohl, M.D.

Response from David Wohl, M.D.

University of North Carolina - Chapel Hill
...It sounds like your doc may be concerned about your virus having some resistance to saquinavir. I think the regimen sounds okay. It is pretty easy and well tolerated in most. You will still have some options in the future Read more »

how long should I expect meds to continue working?

I've been diagnosed 10 years. diagnosed w/aids and pcp 10yrs ago 90 cd4 count viral load off the charts. Probably have been infected 20 yrs(know this because of last at risk behavior was then)Have been on 3 or 4 different med regimens, still on...
Eric Daar, M.D.

Response from Eric Daar, M.D.

UCLA School of Medicine
...regimen, taking the medications consistently and have undetectable viral loads I would assume that the medications will work for as long as you need them. Obviously I can't prove it but I would be very optimistic.You are correct that because of... Read more »

start with saquinavir?

My husband has a CD4=270 and viral load=5000.He was on AZT/Ddc for a year which achieved those numbers andsustained them.His Dr. felt it should be lower and tried AZT/DDi/nevaripine lastmonth and he had a bad reaction to thenevaripine after 2...
Cal Cohen, M.D., M.S.

Response from Cal Cohen, M.D., M.S.

Harvard Medical School
...I don't use saquinavir as a sole protease inhibitor, myself, for reasons that I've discussed before: it achieves poor serum levels and is therefore Read more »
Articles
AIDS InfoNet

Dapsone (Avlosulfon)

...should watch carefully for drug interactions if you are taking dapsone along with the protease inhibitors amprenavir (Ziagen) or saquinavir (Invirase), or the non-nucleoside reverse transcriptase inhibitors delavirdine (Rescriptor) or etravirine... Read more »
The Well Project

HIV Treatment Guidelines

...lamivudine) or Combivir Viramune (nevirapine) and Combivir PI-based regimens Invirase (saquinavir) and low-dose Norvir and Truvada Kaletra once or twice daily and Epzicom or Combivir or... Read more »
AIDS InfoNet

Saquinavir (Invirase)

... What Is Saquinavir? Who Should Take It? What About Drug Resistance? How Is It Taken? What Are the Side Effects? How Does It React With Read more »
AIDSinfo

An Overview of Invirase (Saquinavir mesylate)

... sack-KWIN-uh-vihr MEH-sih-LATE --> Brand Name: Invirase Other Name(s): Ro 31-8959/003 (Saquinavir mesylate), SQV, Saquinavir mesylate, Saquinavir monomethanesulfonate (Saquinavir mesylate) Drug Class: Protease Inhibitors Read more »
Connect With Others

Nothing is working for me, any ideas

Posted by Lifelost, 2 Replies
Not on therapy at the moment, my TC4 count and VL are still good. My problem is that I can not fall asleep. Tried most sleep aid and non has been helpful. I am worried that this is going to weir down my immune pretty quick. Any ideas are... Read more »

RE:how long meds work

Posted by Anonymous, 2 Replies
Hi pals. I was wondering if anyone on the regimen: Viracept+Combivir has any idea how good this regimen is. I want to know what's the average period of time some of you have been on these meds for. I've been taking them for about 7 months and on... Read more »

How long should I wait for testing to work?

Posted by Anonymous, 4 Replies
My girlfriend watched a video in school saying that it could take ten years, while testing every five months, to determine if you have AID's. Is there any truth to that? Read more »

How long does it take for meds to work?

Posted by Anonymous, 3 Replies
...of under 20, the viral load is now 325 and cd4 is 35. I've heard it takes 3-6 months to get the viral load undetectable and longer to get the cd4 back over 200. Does anyone have any experience with going from AIDS back to HIV status? Read more »