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How Long Does Efavirenz Take To Work

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AIDS InfoNet

Efavirenz (Sustiva)

What Is Efavirenz? Efavirenz is a drug used as part of antiretroviral therapy (ART). It is also called Sustiva or Stocrin. It is manufactured by Bristol-Myers Squibb. Generic versions have been tentatively approved under PEPFAR (see Fact Sheet 475 ). Efavirenz is a non-nucleoside reverse transcriptase inhibitor (a "non-nuke" or NNRTI). These drugs stop HIV from multiplying by preventing the reverse transcriptase enzyme from working. This enzyme...
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Efavirenz data - long-lasting negative effects

Hello David,This isn't a question: it's information for you. I note you've been asked about Efavirenz and you have replied:"Efavirenz (brand name Sustiva) does have some relatively common psychiatric side effects, including...
David Fawcett, Ph.D., L.C.S.W.

Response from David Fawcett, Ph.D., L.C.S.W.

South Florida Center for Counseling and Therapy
Thank you for writing. The persistence of your symptoms has clearly been severe. The literature says CNS issues with Efavirenz resolve in "most cases;" your graphic descriptions bring to life those situations when it doesn't. I... Read more »

Combivir/Efavirenz - to - Atripla

I am currently on Combivir/Efavirenz and have been for a while now and my stats all seem good.However the UK has recently authorised Atripla by the PCT (Primary Care Trust) and I wondered as its 1 pill a day if you would recommend me changing and...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
Experience from published studies and the clinic support the notion that often there are less GI complaints from use of Atripla compared to Sustiva + Combivir. Also, the tenofovir in Atripla is more fat friendly than the AZT in Combivir so problems... Read more »

MEDICATION TIMING - HOW MUCH PRECISION NEEDED? ( ATRIPLA AND FOOD, 2011) (EFAVIRENZ AND FOOD,2011)

Dear Dr. Frascino,I am under treatment for six months (tenofovir+lamivudina+efavirenz) with excellent results. No side effects at all and undetectable VL with increasing CD4. However, you might help me with some doubts which cause me a lot of...
Robert J. Frascino, M.D.

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation
Hi.Are you working with an HIV specialist physician? I ask, because the advice you are getting is not accurate.1. Both tenofovir and lamivudine can be taken once per day with or without food. Efavirenz is typically taken at bedtime on an empty... Read more »

concentration and combivir / efavirenz

I have a history of insomnia and problems with my concentration span / anxiety that I have been unable to get resolved with GP. I have also lost over 13kg in body weight in the last 6 months. I have also just started haart (combivir/effavirez) with...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
If you are having problems that are likely related to or aggravated by Sustiva after 4-6 weeks on the drug then a switch to an alternative drug (often a boosted protease inhibitor but sometimes nevirapine) is often a strong consideration depending... Read more »
Connect With Others

Efavirenz: ways to fight its sleep-reduction.

Posted by BrokenWingedBird, 2 Replies
If Efavirenz (and Efavirenz along)is really wrecking your sleep quality, then the only solution is to stop taking Efavirenz (and substitute it with another drug).

However, there are ways to ensure your sleep is as good as possible.

Important discovery: Read more »

How long should I wait for testing to work?

Posted by Anonymous, 4 Replies
My girlfriend watched a video in school saying that it could take ten years, while testing every five months, to determine if you have AID's. Is there any truth to that? Read more »

RE:how long meds work

Posted by Anonymous, 2 Replies
Hi pals. I was wondering if anyone on the regimen: Viracept+Combivir has any idea how good this regimen is. I want to know what's the average period of time some of you have been on these meds for. I've been taking them for about 7 months and on... Read more »

How long does it take for meds to work?

Posted by Anonymous, 3 Replies
After one month on HAAART my loved ones counts are, in comparison to 100000 viral load and cd of under 20, the viral load is now 325 and cd4 is 35. I've heard it takes 3-6 months to get the viral load undetectable and longer to get the cd4 back over... Read more »