How Long Do NNRTIs Take To Work

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Articles

Drug Watch: Next-Generation NNRTIs: Etravirine and Rilpivirine

Why Do We Need More NNRTIs? Leading the Next Generation: Etravirine and Rilpivirine Etravirine: The DUET Studies Rilpivirine Implications for Treatment Selected Sources Even in patients with the most resistant virus, our goal now is full... Read more »

Know Your HIV Drugs: NNRTIs

Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs) NNRTIs are another class of FDA-approved HIV antiviral drugs. There are currently three drugs approved for use in this class. NNRTIs work by targeting the structure of reverse transcriptase... Read more »

Two New NNRTIs Enter the Pipeline

Data on two novel NNRTIs were presented at today's late-breaker session at the International AIDS Conference in Mexico City. After years with little development for this important class of HIV treatments, news on two somewhat promising compounds is... Read more »

Ask the Experts

Sustiva causing resistance to other nNRTIs

Sustiva (efavirenz)-Induced Mutation in Subtype C HIV May Confer Multi-NNRTI ResistanceA mutation at codon 106 in HIV-1 clade C viruses that occurs after exposure to efavirenz appears to result in high-level resistance to other non-nucleotide...

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES

Thanks for pointing out the research.So far, this does not seem like a very common issue-- however, a different mutation at codon 103 is commonly found among persons with clade B HIV (the US, Western Europe flavor)- this mutation usually causes high... Read more »

NNRTIs and lipitor

What is your feeling about Lipitor to lower cholesterol in patients on nnrti regimens? I've been on Sustiva/Truvada for 14 weeks with great results but have been battling high cholesterol for about 10 years, HDL high, LDL low, well controlled...

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine

Lipitor and other statins are not on the absolutely contraindicated list on the FDA approved package insert for sustiva. With anything you just need to be careful and have close followup.... Read more »

How long do newer regimes work?

Hello,first many thanks for your work, this site and especially the questions and answers helped me much since diagnosis. I just wanted to ask how long newer regim work on average for treatment naive patients? Thanks ...

Response from Gerald Pierone, M.D.

AIDS Research and Treatment Center of the Treasure Coast

Well, that depends on the patient. For someone that has perfect adherence and no medication related side effects, they will work indefinitely. For someone with very poor adherence they don't work very well at all. For someone with mediocre... Read more »

how long meds work

dr cohen how long do the meds work? im hiv positive. my dr tells me i can live a full life as long as i adhere to my medications. my viral load is undetectable. my friend who is also hiv positive tells me that the meds only work for 10 years or...

Response from Cal Cohen, M.D., M.S.

Harvard Medical School

Well, it kinda depends on two things - #1; whether you're an optimist or a pessimist, and #2; how good I am at predicting the future. So, here are the issues.It is clear that about 5 years ago, with the principles we now use for treatment,... Read more »

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Connect With Others

How long should I wait for testing to work?

Posted by Anonymous, 4 Replies

My girlfriend watched a video in school saying that it could take ten years, while testing every five months, to determine if you have AID's. Is there any truth to that? Read more »

RE:how long meds work

Posted by Anonymous, 2 Replies

Hi pals. I was wondering if anyone on the regimen: Viracept+Combivir has any idea how good this regimen is. I want to know what's the average period of time some of you have been on these meds for. I've been taking them for about 7 months and on... Read more »

How long does it take for meds to work?

Posted by Anonymous, 3 Replies

After one month on HAAART my loved ones counts are, in comparison to 100000 viral load and cd of under 20, the viral load is now 325 and cd4 is 35. I've heard it takes 3-6 months to get the viral load undetectable and longer to get the cd4 back over... Read more »

Long Term Non-Progressor has questions...

Posted by Anonymous, 2 Replies

I recently had my three month check-up and all of my blood work done at Parkland Hospital in Dallas,TX where I have been a patient for the last three and a half years. Having had an undetectable viral load for about one year and a CD-4 count that... Read more »

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