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How Fast Do T-cells Replicate

Here's a taste of what has to offer on this topic:
Treatment Action Group

HIV Replication and Persistence in T Follicular Helper Cells

Following up on the recent post on T follicular helper cells(TFH) , a study published on December 17th in the Journal of Experimental Medicine reports that TFH represent a major site of HIV replication andpersistence. The finding is not... Read more »

HIV Found to Replicate Outside CD4 Cells; Discovery Gives Insight Into HIV-related Dementia

In an intriguing new study published last week in PLoS Pathogens , researchers discovered the first solid proof that HIV can replicate itself in cell types other than CD4 cells. The finding potentially opens an important window on our understanding... Read more »
Henry J. Kaiser Family Foundation

Suppression of Human Protein Reduces HIV's Ability to Enter T Cells, Replicate, Study Finds

Researchers have found that suppressing the human protein ITK in CD4+ T cells reduces HIV's ability to enter the cells and replicate, according to an NIH study published Monday in the Proceedings of the National Academy of Sciences , Reuters ... Read more »
Ask the Experts

viral replication

how fast does the virus replicate in human body after infection. what will be the viral load of a person after one year of infection...
Mark Holodniy, M.D., F.A.C.P., C.I.C.

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine
Within a week of infection the virus can be measured. The viral load after one year is very variable and depends on the strain of virus and a person's underlying immune system. It can range from undetectable to several 100,000s after one year.... Read more »

lymphocytes and viral replication

1)In the context of HIV/HepC co-infection, can T cells be lost without the HIV virus replicating? Or is it the replication itself that depletes the T cells?2)If the HIV virus is replicating, is there always a detectable viral burden in serum, or a...
Barbara McGovern, M.D.

Response from Barbara McGovern, M.D.

Tufts University School of Medicine
Most, but not all, T cell destruction is by HIV itself. In HIV/HCV patients some studies suggest that T cell responses to HIV medicines are not as good as in HIV patients without Hepatitis C. Some have wondered whether chronic hepatitis C may be a... Read more »

Non CD4 replication

HIV uses CD4 cells to replicate and is blocked by HAART from doing this explaining a VL UD when it's successful. But, is there any replication going on in the non CD4 cells that sequester HIV? like lymphnodes, and other tissues? and if so are...
Mark Holodniy, M.D., F.A.C.P., C.I.C.

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine
Great question. First, there are CD4+ t cells and monocytes and other cells with CD4 receptors that exist in lymph nodes and other organs, and are not just circulating in the blood. HIV can infect some of these other types of cells and replicate at... Read more »

Viral Replication

I am confused about viral replication. The current antiretiroviral drugs prevent replication. However, when the meds are stopped is the virus still present in the infected cell and able to start replicating again?...
Renslow Sherer, M.D.

Response from Renslow Sherer, M.D.

University of Chicago Hospitals
Yes to both questions. The current antiretroviral drugs are 'static' drugs, i.e. they don't kill the virus, but they do prevent replication. Fortunately, the consequences of stopping replication are prolonged length of life and a... Read more »
Connect With Others

See,I told you HIV replicates a cell's DNA TO RNA

Posted by Anonymous, 1 Reply
The below is plagerized from Gallant ( the guru!)
I know that the present antiretroviral medications do not actually kill the virus.
However, if the medications inhibit the virus from reproducing, doesn't the virus die
by... Read more »

Worried..T-Cells count going down fast!

Posted by Overstressed, 4 Replies
I was tested postive in 2003 and when I went in for my frist T-Cell count and Viral Load I was not sure what to expect..I started @1041 T-Cell and viral load 45,000 and of course I would go in and get my count every 3 months . My T-Cells would be... Read more »

Is life moving too fast?

Posted by Anonymous
Someone emailed me this and what struck me about it was how I responded to it. After fearing for my life now for a few weeks things get put into perspective. I could care less about half the "important" and "urgent" things I used to worry about and... Read more »


Posted by DUDE
Subject: SECOND POST-Virus Replication & OTHER Things
Fellas fellas fellas,,,,
It's certainly time to move one. These HIV tests are very sensative. If you are infected with the HIV virus (or any virus for that matter)
the human body produces... Read more »